| Japanese |
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| Title | 回転型ガンマカメラの心臓イメージングへの応用 - 第6報 : 運動負荷時・再分布時のタリウム心筋ECTの検討 - |
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| Subtitle | 原著 |
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| Authors | 玉木長良*, 米倉義晴*, 向井孝夫*, 藤田透*, 湊小太郎*, 森田陸司*, 鳥塚莞爾*, 野原隆司**, 鈴木幸園**, 田巻俊一**, 門田和紀**, 神原啓文**, 河合忠一**, 石井靖*** |
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| Authors(kana) | |
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| Organization | *京都大学医学部放射線核医学科, **第三内科, ***福井医科大学放射線科 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 9 |
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| Page | 1299-1306 |
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| Year/Month | 1983/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 健常人8例, 虚血性心疾患 (CAD) 48例の計56例に, 運動負荷時および再分布時にタリウムECTを施行し, 冠動脈領域別に欠損の有無を検出した. 欠損を認めたのはCAD 48例中45例 (94%) , 罹患冠動脈95本中78本 (82%) であった. また罹患冠動脈数を正しく推定できたのは, 1枝病変78%, 2枝病変69%, 3枝病変53%と本数が増える程低下した. これにROI法による定量的解析法を加えると, 3枝病変正診率は76%と上昇し, 罹患冠動脈の検出率も92%と改善したが, やや読み過ぎの傾向もみられた. 罹患冠動脈別のsensitivityはRCA 85%, LAD 90%, LCX 63%であり, specificityはいずれも90%を越えた. X線左室造影所見と対比すると, 欠損のない区域では94%が正常な壁運動を呈した. 著明な壁運動異常を呈したのは再分布のみられた欠損部の15%に対し, 再分布のみられない部位の63%に達した. 運動負荷ECTは, CADの診断や罹患冠動脈の検出に優れ, 再分布時ECTとの併用により心筋viabilityの評価が可能と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Thallium-201, emission computed tomography, rotating gamma camera, coronary artery disease, exercise test |
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| English |
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| Title | Cardiac Emission Computed Tomography (ECT) Using a Rotating Gamma Camera (6) Evaluation of Stress and Redistribution ECT Imaging |
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| Subtitle | Original Articles |
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| Authors | Nagara TAMAKI*, Yoshiharu YONEKURA*, Takao MUKAI*, Toru FUJITA*, Kotaro MINATO*, Rikushi MORITA*, Kanji TORIZUKA*, Ryuji NOHARA**, Yukinoso SUZUKI**, Shunichi TAMAKI**, Kazunori KADOTA**, Hirofumi KAMBARA**, Chuichi KAWAI**, Yasushi ISHII*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine, and**Department of Internal Medicine, Kyoto University Medical School, ***Department of Radiology, Fukui medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 9 |
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| Page | 1299-1306 |
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| Year/Month | 1983/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The value of stress and redistribution thallium-201 emission computed tomography (ECT) for detecting individual coronary artery involvement was analyzed in 58 cases, including 8 normal cases and 48 cases with angiographically proved coronary artery disease (CAD) . Perfusion defect was observed in 45 of the 48 cases with CAD (94%) and in 78 of the 95 diseased coronary arteries (82%) . Number of diseased coronary arteries was accurately predicted in 78% of those with single vessel disease and 69% of those with two-vessel disease, but only in 53% of those with three-vessel disease. Quantitative assessment of thallium distribution and washout rate improved the sensitivity for detection of diseased vessels (95%) and accuracy for prediction of three vessel disease (76%) . The sensitivity for detection of individual coronary artery involvement was 85% for RCA, 90% for LAD, and 63% for LCX The specificity was also high (90% for RCA, 93% for LAD, and 100% for LCX. ) Segmental analysis of ECT imaging was comparatively assessed with the results of contrast left ventriculography. Marked wall motion abnormalities (dys-or akinesis) were seen in 15% of the segments with transient perfusion defect, but in 63% of those with persistent perfusion defect. We conclude that stress and redistribution thallium ECT imaging is a sensitive and specific tool for predicting individual coronary artery involvement and regional myocardial viability. |
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| Practice | Clinical medicine |
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| Keywords | Thallium-201, emission computed tomography, rotating gamma camera, coronary artery disease, exercise test |
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