| Japanese |
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| Title | 123I ヒプル酸ナトリウムによる移植腎機能検査 - 局所レノグラムおよび腎血流イメージについて - |
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| Subtitle | 原著 |
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| Authors | 池平博夫*, 内山暁*, 有水昇**, 桂井浩**, 植松貞夫***, 宇野公一***, 舘野之男****, 宍戸文男****, 永田松夫*****, 落合武徳*****, 佐藤博***** |
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| Authors(kana) | |
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| Organization | *山梨医科大学放射線医学教室, **千葉大学医学部放射線医学教室, ***千葉大学附属病院放射線部, ****放射線医学総合研究所臨床研究部, *****千葉大学医学部第二外科学教室 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 8 |
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| Page | 1163-1173 |
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| Year/Month | 1983/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」移植腎機能の評価に主として尿細管機能を表す123I-ヒプル酸ナトリウム (123I-IOH) を用いて, ファンクショナルイメージ検査法を考案した. 移植腎18例は移植後数週のものから数年のものまでにわたる. 対照の2例を加えて計20例に123I-IOH約37MBqを投与し, 22回の検査を行った. ファンクショナルイメージは4種類のパラメータを用意し, それぞれの有用性を検討した. 結果として, 初期分泌相の1分間カウントをパラメータとし, 別にわれわれ独自の方法で求めた腎有効血流量 (ERBF) を乗じたファンクショナルイメージが最も移植腎尿細管機能を反映するものとして有用であった. ERBFは, RI静注後5分と25分後に採血, 血中RI濃度を0時に外挿した値などから求めた, このファンクショナルイメージは, 血中BUN値や主として糸球体濾過機能を表す血中クレアチニン値とともに高感度の移植腎機能検査法として役立つものと思われる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Transplanted kidney, 123I-ortho-iodo-hippurate, Effective renal blood flow, Regional renogram, Functional image |
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| English |
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| Title | Evaluation of Transplanted Kidney Function with 123I-Ortho-Iodo-Hippurate |
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| Subtitle | |
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| Authors | Hiroo IKEHIRA*, Guio UCHIYAMA*, Noboru ARIMIZO**, Hiroshi KATSULAI**, Sadao UEMATSU***, Kimiichi UNO***, Yukio TATENO****, Fumio SHISHIDO****, Matsuo NAGATA*****, Takenari OCHIAI*****, Hiroshi SATO***** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Yamanashi University School of Medicine, **Department of Radiology, Chiba University Sachool of Medicine, ***Depatment of Radiology, Chiba University Hospital, ****Division of Clinical Research, NIRS, *****Department of 2nd Surgery, Chiba University School of Medicine Chiba |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 8 |
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| Page | 1163-1173 |
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| Year/Month | 1983/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A non-invasive study for evaluating transplanted kidney function was developed using 123I-ortho-iodo-hippurate (OIH) with radionuclide image processing technique. Twenty patients with transsplanted kidneys in few weeks to several years after transplantation were imaged after the administration of 1mCi 123I-OIH. Functional images with 4 kinds of parameters were processed and evaluated. The one with a parameter of regional counts in early secretory phase of renogram, multiplied by the effective renal blood flow (ERBF) , seemed to be the most promissing indicator for the function of transplanted kdneys. The ERBF was calculated by counting 5-and 25-minute blood samples. The functional images representing regional function of blood flow and secretion of kidneys add another valuable information to the conventional serum creatinine and BUN values. |
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| Practice | Clinical medicine |
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| Keywords | Transplanted kidney, 123I-ortho-iodo-hippurate, Effective renal blood flow, Regional renogram, Functional image |
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