Japanese
Title冠動脈病変の診断における運動負荷RIアンジオグラフィおよび運動負荷心筋シンチグラフィの有用性の検討
Subtitle原著
Authors都田裕之*, 河合直樹*, 岡田充弘*, 志貴一仁*, 都築雅人*, 近藤照夫*, 外畑巌*
Authors(kana)
Organization*名古屋大学医学部第一内科
Journal核医学
Volume20
Number6
Page831-840
Year/Month1983/7
Article原著
Publisher日本核医学会
Abstract「要旨」労作狭心症患者40例および健常者7例について運動負荷RIアンジオグラフィ (RNA) および運動負荷心筋シンチグラフィ (MPI) の冠動脈病変診断能を検討し, 同時に運動負荷12誘導心電図試験 (ECG) の成績と比較した. 狭心症群全体における冠動脈有意狭窄枝の存在診断では, RNA, MPIおよびECGの有病正診率はおのおの90%, 80%および88%, 無病正診率はいずれも100%であった. 第1群 (LADの1枝病変6例) および第2群 (RCAまたはLCXの1枝または2枝病変12例) における冠動脈有意狭窄枝の部位診断では, RNAおよびMPIの有病正診率はLAD病変に対してはともに100%, RCAまたはLCX病変に対してはともに42%であった. 第3群 (その他22例) における冠動脈有意狭窄枝の部位診断では, RNAおよびMPIの有病正診率は主病変枝および同等病変枝に対しては高く, 非主病変枝に対しては低かった. 両RIイメージング法は冠動脈病変の診断に有用と考えられた.
Practice臨床医学：一般
Keywordsexercise stress radionuclide angiocardiography, exercise stress thallium-201 myocardial perfusion imaging, coronary artery disease
English
TitleDiagnostic Reliabilities of Exercise Stress Radionuclide Angiocardiography and Thallium-201 Myocardial Perfusion Imaging in Patients with Effort Angina
SubtitleOriginal Articles
AuthorsHiroyuki MIYAKODA, Naoki KAWAI, Mitsuhiro OKADA, Kazuhito SHIKI, Masato TSUZUKI, Teruo KONDO, Iwao SOTOBATA
Authors(kana)
OrganizationThe First Department of Internal Medicine, Nagoya University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume20
Number6
Page831-840
Year/Month1983/7
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] The diagnostic reliabilities of exercise stress radionuclide testings for diagnosing coronary artery disease (CAD) were evaluated in 40 effort angina patients without previous myocardial infarction and 7 normal subjects. Patients with effort angina were divided into three groups : group 1 (6 patients with single vessel disease of left anterior descending artery [LAD] ) , group 2 (12 patients with single or double vessel disease involving right coronary artery [RCA] and/or left circumflex artery [LCX] ) and group 3 (the remaining 22 patients) . Radionuclide left ventricular angiocardiograms (RNA) in the right anterior oblique projection were obtained with the first-pass method at rest and immediately after exercise with a supine bicycle ergometer. and left ventricular ejection fraction and wall motion were evaluated. Exercise stress thallium-201 myocardial perfusion imaging (MPI) with an upright bicycle ergometer was obtained, and the quantitative analysis of regional 201Tl myocardial uptake ratio and washout rate was made. The sensitivity of RNA (90%) , MPI (80%) , or both tests in combination (95%) for detecting CAD was nearly equivalent to that of exercise stress 12-lead electrocardiography (ECG) (88%) in the whole patients. It was higher in groups 1 and 3 than in group 2. The specificity was 100% for RNA, MPI or ECG. For detecting LAD disease in groups 1 and 2, the sensitivity of RNA or MPI was 100%, and the specificity was also 100%. For detecting RCA and/or LCX disease in groups 1 and 2, the sensitivity of RNA or MPI was 42%, and the specificity was 100%. In group 3 the sensitivity of the combination of RNA and MPI was higher for detecting the most severely diseased artery (100% for LAD disease, and 88% for RCA and/or LCX disease) but was quite low for detecting less severely diseased ones (25%) . We conclude that exercise stress radionuclide angiocardiography and thallium-201 myocardial perfusion imaging are useful for diagnosing the presence or absence of CAD and also the diseased coronary arteries.
PracticeClinical medicine
Keywordsexercise stress radionuclide angiocardiography, exercise stress thallium-201 myocardial perfusion imaging, coronary artery disease

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