| Japanese |
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| Title | 先天性心疾患におけるマルチゲート心血液プール・データのフーリエ解析による検討 - (1) 左右短絡疾患, 特に心室中隔欠損症を中心にして - |
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| Subtitle | 原著 |
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| Authors | 竹田寛*, 前田寿登*, 山口信夫*, 中村和義*, 中川毅*, 田口光雄*, 桜井実*, 青木謙三* |
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| Authors(kana) | |
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| Organization | *三重大学医学部放射線科, **小児科, ***松阪市民病院小児科 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 6 |
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| Page | 803-814 |
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| Year/Month | 1983/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」左右短絡を有する先天性心疾患を対象に, マルチゲート法により, 各画素および両心室の時間アクティビティ曲線を求め, それぞれフーリエ解析し, 一次項の位相角および振幅を算出した. 正常人 (18例) では, 心拍数に関係なく, 左右心室の位相角差 [D (Phase) ] は, 平均1.7±5.8度, 左室振幅に対する右室振幅の比 [R (amp) ] は, 0.54±0.20であった. D (Phase) は, 心室中隔欠損症 (VSD) (22例) で, 肺循環体循環血流比 (Qp/Qs) に比例して増加し (r=0.899, p<0.001) , Qp/Qs>2.0では, 18度以上の高度の右室位相角の遅延をみた. R (amp) は, 動脈管開存症 (9例) では小さく, 心房中隔欠損症 (11例) では著明に増大したが, VSDでは正常範囲内の値を示した. 各画素ごとの位相角および振幅によるファンクショナル・イメージは, これら疾患の鑑別だけでなく, VSDの位置を判定しうる場合もあり, 臨床上有用と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | multi-gated blood-pool data, Fourier analysis, congenital heart disease, left-to-right shunt |
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| English |
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| Title | Fourier Analysis of Multi-gated Blood-pool Data in Patients with Congenital Heart Disease - (1) Assessment of Disease with Left to Right Shunt, Especially Ventricular Septal Defect - |
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| Subtitle | Original Articles |
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| Authors | Kan TAKEDA*, Hisato MAEDA*, Nobuo YAMAGUCHI*, Kazuyoshi NAKAMURA*, Tsuyoshi NAKAGAWA*, Mitsuo TAGUCHI*, Minoru SAKURAI**, Kenzo AOKI*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, **Department of Pediatrics, Mie University School of Medicine, ***Department of Pediatrics, Matsusaka Municipal Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 6 |
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| Page | 803-814 |
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| Year/Month | 1983/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The ventricular emptying performance in patients with congenital heart disease with left to right (L-to-R) shunt was investigated by temporal Fourier analysis of multi-gated cardiac blood-pool data. Functional images are constructed with parameters of each pixel's phase angle and amplitude at fundamental frequency. Using global time-activity curves of both ventricles, phase angle and amplitude of left and right ventricles (LV and RV) were computed. Values of interventricular phase difference [D (phase) ] and amplitude ratio of RV to LV [R (amp) ] were calculated in individual cases. In 18 subjects with normal cardiac function, mean (+-standard deviation) values of D (phase) was 1.7+-5.8 degree and that of R (amp) was 0.54+-0.20, respectively regardless of heart rate. In 22 patients of ventricular septal defect (VSD) with L-to-R shunt, D (phase) became larger in proportion to the ratio of pulmonary to systemic blood flow (Qp/Qs) (r=0.899, p<0.001) . Especially, in those with large L-to-R shunt (Qp/Qs>2.0) , significant RV phase lag over 18 degrees was recognized and types of VSD might be possible to be differenciated by phase images. In 9 patients with patent ductus arteriosus (PDA) , no RV phase delay was seen. Mean value of R (amp) was considerably smaller in patients with PDA and significantly larger in 11 patients with atrial septal defect (ASD) , as compared with that of subjects with normal cardiac functions. However, cases with VSD took the values within normal range. This method is highly valuable for pathophysiologic investigation and differential diagnosis of congenital heart disease with L-to-R shunt. |
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| Practice | Clinical medicine |
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| Keywords | multi-gated blood-pool data, Fourier analysis, congenital heart disease, left-to-right shunt |
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