| Japanese |
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| Title | 肺癌の局所換気評価のための133Xeガス洗い出し法と81mKrガス連続吸入法の比較検討 |
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| Subtitle | 原著 |
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| Authors | 楢林勇*, 杉村和朗*, 大西隆二**, 末松徹**, 伊藤一夫**, 福川孝*, 井上善夫**, 木村修治** |
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| Authors(kana) | |
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| Organization | *神戸大学医学部中央放射線部, **放射線科 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 5 |
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| Page | 675-680 |
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| Year/Month | 1983/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」肺癌36例を対象として同一症例に133Xeガスと81mKrガスによる換気検査を行い, 99mTc-MAAによる血流イメージとも対比しつつ肺癌の局所換気評価について比較検討した. イメージ上局所換気障害を81mKrガス連続吸入法がより鋭敏に検出したもの8例, 133Xeリテンションの方がよく描画したものが4例であり, 他はほぼ同等であった. 患側肺において, 133Xe洗い出し曲線からheight over area法で算出したMTTは81mKrガス連続吸入による%Vとは必ずしも相関しなかった. また, 81mKrガスによる%Vと99mTc-MAAによる%Qとの関係はr=0.852, p<0.001であったが, MTTと%Qの相関は低かった. これは MTTの算出には個々の症例で適正なバックグラウンド計数率の除去を要するため, 実際上局所換気障害の指標としてのMTTの定量化が困難であることを示した. |
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| Practice | 臨床医学：一般 |
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| Keywords | Regional ventilation, Xe-133 washout method, Kr-81m continuous inhalation method, Lung cancer |
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| English |
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| Title | Evaluation of Regional Ventilation in Patients with Lung Cancer : A Comparison with Xenon-133 and Krypton-81m Studies |
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| Subtitle | |
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| Authors | Isamu NARABAYASHI, Kazuro SUGIMURA, Ryuji ONISHI, Toru SUEMATSU, Kazuo ITO, Takashi FUKUGAWA, Yoshio INOUE, Shuji KIMURA |
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| Authors(kana) | |
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| Organization | Department of Radiology, Kobe University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 5 |
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| Page | 675-680 |
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| Year/Month | 1983/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Ventilation studies with Xenon-133 gas and Krypton-81m gas, and perfusion imaging with Tc-99m MAA were performed on the same day in 36 patients with lung cancer. Initially Xenon-133 ventilation study consisting of single-breath, equilibrium and sequential washout images was carried out in the sitting position. This was followed immediately by Krypton-81m ventilation and Tc-99m MAA perfusion imaging. The computer calculated mean value of the transit time of Xenon-133 equilibrium washout curve using height over area method in the affected lung by the tumor. The values of %V with Krypton-81 m during tidal breathing expressed as percentages of the tumor-bearing lung for the total lung were not always related to the mean values of the transit time with Xenon-133. On the other hand, the correlation coefficient between %V with Krypton-81m and %Q with Tc-99m MAA was 0.852. There were some mismatched cases between ventilation and perfusion in lung cancer. The mean value of the transit time of Xenon-133 washout curve seemed to have a limited role in the quantitative assessment of regional ventilation because of affinity of Xenon to fatty tissue. |
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| Practice | Clinical medicine |
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| Keywords | Regional ventilation, Xe-133 washout method, Kr-81m continuous inhalation method, Lung cancer |
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