| Japanese |
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| Title | 虚血性心疾患における肺内血流分布の特徴 - デジタル肺血流像 (DPI) による評価 - |
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| Subtitle | 原著 |
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| Authors | 田中健*, 木全心一*, 関口守衛*, 広沢弘七郎*, 牧正子**, 日下部きよ子**, 田崎瑛生**, 山崎統四郎*** |
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| Authors(kana) | |
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| Organization | *東京女子医科大学日本心臓血圧研究所, **放射線科, ***放射線医学総合研究所 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 5 |
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| Page | 641-650 |
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| Year/Month | 1983/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」虚血性心疾患における肺内血流再分布をデジタル肺血流像 (DPI) を用いて検討した. DPIの定量化は右肺鎖骨中線上の第三肋間と肺底部間のカウント比 (pulmonary redistribution index PRI) によって行った. 対象とした39症例はPRIによってGrade-0 (G-0, 0.7>PRI), G-1 (1>PRI≧0.7), G-2 (PRI≧1)の三段階に分類し得た (平均±標準偏差). G-0 (19例, mPA, 13.7±1,8mmHg, mPw; 8.0±2.2mmHg, EF; 56.6±12.8%) G-1 (14例, mPA, 18.5±3.5mmHg, mPw; 12.8±3.3mmHg, EF; 45,2±8.6%) G-2 (6例, mPA, 42.3±4.7mmHg, mPw; 26.5±4.7mmHg, EF; 13.3±37%) mPA: 平均肺動脈圧, mPw: 平均肺動脈楔入圧, EF: 駆出率. 各パラメター間の差は有意であった. PRI≧0.7が異常肺内血流分布と考えられた. PRI<1に対してPRI=0.54+0.074 mPw/CO (r=0.75) の良好な相関関係が得られ肺血行動態パラメターがPRIより推定し得る可能性が得られた. PRI≧1の状態は例外なく難治性心不全の状態であった (specificity 100%). 虚血性心疾患の肺内血流再分布異常は僧帽弁狭窄症におけるほど著明ではなかった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Digital perfusion images (DPI), Coronary artery disease, Pulmonary redistribution index (PRI) |
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| English |
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| Title | Characteristics of Pulmonary Perfusion in Coronary Artery Disease Noninvasive Estimation with Digital Perfusion Images (DPI) |
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| Authors | Takeshi TANAKA*, Shinichi KIMATA*, Morie SEKIGUCHI*, Koshichiro HIROSAWA*, Masako MAKI**, Kiyoko KUSAKABE**, Eisei TAZAKI**, Toshiro YAMAZAKI*** |
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| Authors(kana) | |
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| Organization | *Heart Institute Japan, **Department of radiology, Tokyo Womans' Medical College, ***National Institute of Radiology |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 5 |
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| Page | 641-650 |
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| Year/Month | 1983/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] To determine whether distribution of pulmonary perfusion can be used as a noninvasive method to estimate any of hemodynamic changes in patients with coronary artery disease (CAD), Tc-99m-MAA digital perfusion images (DPI) were evaluated in 39 patients with CAD. DPI were estimated by the 3rd intercostal space to base count ratio (pulmonary redistribution index; PRI). Patterns of DPI were classified to 3 grades according to PRI, i.e. Grade-0 (G-0) (0.7>PRI), G-1 (1>PRI>=0.7) and G-2 (PRI>=1). This classification proved to be hemodynamically significant. G-0 (mPA; 13.7+-1.8 mmHg, mPw; 8.0+-2.2 mmHg, EF; 56.6+-12.8%), G-1 (mPA; 18.5+-3.5 mmHg, mPw; 12.8+-3.3 mmHg, EF; 45.2+-8.6%), G-2 (mPA; 42.3+-4.7 mmHg, mPw; 26.5+-4.7 mmHg, EF; 13.3+-3.7%). mean+-SD, EF; ejection fraction, mPA; mean pulmonary artery pressure, mPw; mean PA wedge pressure. The specificity of PRI 1 for severe cardiac dysfunction [mPA>=30 mmHg, mPw>=20 mmHg, EF<=25%] was 100% (33/33). PRI was considered abnormal if greater than 0.7. In patients with PRI<1 (14+19=33 cases) PRI correlated better with mPw/CO (r=0.75) than with mPw (r=0.68). The sensitivity of PRI for mPw/CO>=2 mmHg/L/m was 91% (10/11) and the specificity was 82% (18/ 22). It is concluded that severe cardiac dysfunction can be easily detected by DPI. It is possible to estimate mPw/CO from PRI. [CO; cardiac output (L/m).]. |
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| Practice | Clinical medicine |
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| Keywords | Digital perfusion images (DPI), Coronary artery disease, Pulmonary redistribution index (PRI) |
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