Japanese
Title肥大型心筋症における 201Tl 心筋シンチグラムの検討 - 201Tl 右室心筋摂取率について -
Subtitle短報
Authors宮永一*, 足立晴彦*, 杉原洋樹*, 鳥居幸雄*, 勝目紘*, 伊地知浜夫*
Authors(kana)
Organization*京都府立医科大学第二内科
Journal核医学
Volume20
Number3
Page329-333
Year/Month1983/4
Article報告
Publisher日本核医学会
Abstract「I. 緒言」 近年 201Tl 心筋シンチグラム (以下201Tl-MPI) は虚血性心疾患の診断に賞用され, 必須のものとなっている. 一方201Tl-MPIは心形態の診断においても有用であることが報告されてきた. 肥大型心筋症 (以下HCM) においても201Tl-MPIで左心室壁の肥厚が認められ診断に有用とされるが, 左心室肥厚を201Tl-摂取率より定量的に判定しようとする試みも報告されている. 他方, 最近超音波心断層図を用いてHCMに右心室の壁肥厚を認めたとの報告がみられ, 従来左心室病変のみに注目されていたHCMにおける右心室の関与を示唆する興味ある知見と考えられる. 今回私どもは201Tl-MPIを用いてHCMにおける右心室病変の検出を目的として 201Tl 右室心筋摂取率を検討したので報告する.
Practice臨床医学：一般
KeywordsRV fractional myocardial uptake of 201Tl, Hypertrophic cardiomyopathy, 201Tl myocardial scintigraphy
English
TitleIncrease of RV Fractional Myocardial Uptake of 201Tl in Patients with Hypertrophic Cardiomyopathy (HCM)
Subtitle
AuthorsHajime MIYANAGA, Haruhiko ADACHI, Hiroki SUGIHARA, Yukio TORII, Tomi WATANABE, Hiroshi KATUME, Hamao IJICHI
Authors(kana)
OrganizationSecond Department of Internal Medicine, Kyoto Prefectural University of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume20
Number3
Page329-333
Year/Month1983/4
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Right and left ventricular uptake of 201Tl was measured for the detection of hypertrophic involvement of right ventricle (RV) in the patients with hypertrophic cardiomyopathy. Thirty subjects [11 were normal, 10 were hypertensive heart disease (HHD) and 9 were HCM] were evaluated by submaximum exercise 201Tl myocardial scintigraphy and fractional myocardial uptake of 201Tl in both ventricles was obtained with method reported by Ishi, et al. in 1976. The LV fractional myocardial uptake in HCM (6.41+-1.77%) (mean+-1 sd) was significantly greater than in HHD (4.90+-0.84%, p < 0.05) and in normal subjects (3.84+-0.54%, p < 0.01). And the RV fractional myocardial uptake in HCM (2.28+-0.82%) was also greater than in HHD (1.56+-0.35%, p < 0.05) and in normal subjects (1.39+-0.37%, p < 0.01). But fractional myocardial uptake ratio of RV to LV showed no significant difference in three groups. Because the fractional myocardial uptake of 201Tl was assumably proportional to the fractional myocardial blood flow to cardiac output (MBF/CO) according to the indicator fractional principle, and increase of myocardial blood flow was thought to be mainly due to increase of myocardial mass, so the results of this study indicate that, in HCM, there were not only increase of myocardial blood flow but also myocardial muscle mass in both ventricles. We concluded that the measurement of RV fractional myocardial uptake was valuable for the evaluation of RV involvement in HCM.
PracticeClinical medicine
KeywordsRV fractional myocardial uptake of 201Tl, Hypertrophic cardiomyopathy, 201Tl myocardial scintigraphy

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