English
TitleReappraisal of Radionuclide Liver Scans for Preoperative Gastric Cancer Patients
SubtitleOriginal Articles
AuthorsMakoto KONDO*, Yoshio YONAHARA, Shoji YAMASHITA*, Yutaka ANDO*, Makoto MOHRI, Shigeru KOSUDA, Hidekazu MASAKI**, Tatsuo YOSHIOKA
Authors(kana)
OrganizationThe Departments of Nuclear Medicine and Radiology, National Tokyo Second Hospital, Present Address:*Department of Radiology. Keio University School of Medicine., **Department of Radiology, National Children's Hospital.
JournalThe Japanese Journal of nuclear medicine
Volume20
Number3
Page309-312
Year/Month1983/4
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Abstract] Radionuclide liver scans were obtained in 89 preoperative patients with gastric cancer. Eight showed definite defects on liver scans. At laparotomy, 14 patients were found to have liver involvement secondary to gastric cancer. The sensitivity of liver scans to predict liver involvement is 57% (8/14), and the specificity is 100% (75/75). The patients with definite defects on liver scans had a lower rate of palliative resection of the primary tumors (2/8) than the patients with liver involvement and no scan abnormality (4/6). The patients with advanced lesions but without liver involvement had the highest probability of resecting the primary tumors (57/63 : 47 radical, and 10 palliative). Normal serum levels of liver chemistries did not preclude the presence of defects on liver scans. Additional three patients were found to have cirrhosis of the liver solely based on liver scans, which was confirmed at laparotomy. Radionuclide liver scans can predict liver involvement with very few false positives, and may discriminate patients unsuitable for laparotomy even with palliative intent.
PracticeClinical medicine
KeywordsRadionuclide liver scan, gastric cancer, surgery, liver chemistry
Japanese
Title術前胃癌患者における肝スキャンの再検討
Subtitle原著
Authors近藤誠*, 与那原良夫, 山下昌次*, 安藤裕*, 毛利誠, 小須田茂, 正木英一**, 吉岡達夫
Authors(kana)
Organization国立東京第二病院核医学科・放射線科, *現慶応義塾大学医学部放射線医学教室, **現国立小児病院放射線科
Journal核医学
Volume20
Number3
Page309-312
Year/Month1983/4
Article原著
Publisher日本核医学会
Abstract「要旨」 胃癌症例における肝スキャンの意義を再検討する目的で, 手術予定症例に肝スキャンを行い, その読影結果と手術所見と血清生化学検査結果とを比較した. 89例中8例にはっきりした欠損像を得た. 開腹時に14例に胃癌による浸潤・転移を肝に認めた. 肝スキャンのsensitivityは57% (8/14), specificity は100% (75/75) であった. 肝病変のあった14例中では, 肝スキャン陽性群の方が姑息的胃切除の施行率が低かった (2/8 vs. 4/6). 進行癌でも肝スキャン陰性例では胃切除の施行率が高かった (57/63 ; 根治的47例, 姑息的10例). 血清肝酵素値が正常であっても, 肝スキャン陽性像を得ることがある. 他の3例では肝スキャンによって肝硬変が術前に診断できた. 肝スキャンの特異性を高くすることは可能で, 開腹に適さない胃癌症例を選び出せるかもしれない.
Practice臨床医学:一般
KeywordsRadionuclide liver scan, gastric cancer, surgery, liver chemistry

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