Japanese
Titleフーリエ高次解析法を用いたマルチゲート心血液プール像の壁運動の定量評価 - (2) シミュレーションカーブによる基礎的検討 -
Subtitle原著
Authors玉木長良*, 向井孝夫*, 湊小太郎*, 林信成*, 藤田透*, 森田陸司*, 浜中大三郎*, 石井靖**, 米倉義晴*, 鳥塚莞爾*
Authors(kana)
Organization*京都大学医学部放射線核医学科, **福井医科大学放射線科
Journal核医学
Volume20
Number3
Page301-307
Year/Month1983/4
Article原著
Publisher日本核医学会
Abstract「要旨」 左室容量曲線モデルに種々の統計雑音と時間的変動を加えたシミュレーション曲線を作成し, フーリエ近似を行い算出された収縮期および拡張期の指標を, モデル曲線の値と比較することにより, 近似の精度を検討した. フーリエ1次項近似では曲線近似が不十分であり, 4次項ではカウントが少なくなると誤差を生じる傾向にあり, フーリエ2次項または3次項の近似が最も高い精度で指標を算出した. 収縮期の指標 (TES, PER, TPE) は統計変動や時間的変動の影響を受けにくかった. 拡張早期の指標 (PFR, TPF) は時間的変動の影響を受けやすいが誤差は位相で50msec, 変化率で10%以内であり, 臨床利用が可能と考えられた. 他方拡張後期の指標 (AK, TAK) は誤差が大きかった. フーリエ2次または3次級数を用いて, 左室および左室局所の容量曲線を近似することにより, 収縮期と拡張早期を分離して, 比較的高い精度で算出でき, 心機能, 局所心機能の評価に利用可能と考えられた.
Practice臨床医学:一般
Keywordsgated blood pool imaging, Fourier transform, phase analysis, simulation study, higher order harmonics
English
TitleQuantitation of Global and Regional Cardiac Performance by Phase Analysis Using Higher Order Harmonics - (2) Cardiac Simulation Study -
SubtitleOriginal Articles
AuthorsNagara TAMAKI*, Takao MUKAI*, Kotaro MINATO*, Nobushige HAYASHI*, Toru FUJITA*, Rikushi MORITA*, Daizaburo HAMANAKA*, Yasushi ISHII**, Yoshiharu YONEKURA*, Kanji TORIZUKA*
Authors(kana)
Organization*Department of Radiology and Nuclear Medicine, Kyoto University Medical School, and ** Department of Radiology, Fukui Medical School
JournalThe Japanese Journal of nuclear medicine
Volume20
Number3
Page301-307
Year/Month1983/4
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] In order to determine the optimum order harmonics of the Fourier transform, we constructed simulation model of cardiac volume curve in equilibrium gated blood-pool study. Statistical noise from Poisson random (enddiastolic counts : EDC) and temporal noise from Gaussian random (standard deviation : σ) were added to an ideal curve to simulate various volume curves. The first through the 4th order harmonics of Fourier transform was performed to obtain the fitted curves. The systolic indices (time to end systole : TES ; peak ejection rate : PER ; and time to PER : TPE), the early diastolic indices (peak filling rate : PFR ; and time to PFR : TPF), and late diastolic indices (atrial kick : AK ; and time to AK : TAK) were calculated from each fitted curve. The fundamental Fourier analysis was not suited to calculate the systolic and diastolic indices separately. The 4th-order harmonics was unsatisfactory, because high frequency noises can not be excluded in case of small EDC (200 to 400 counts). The systolic indices were reliable even in case of small EDC and large σ (up to 15%). Although the early diastolic indices varied moderately when temporal noise was large (σ = 15%), these values were clinically acceptable (less than 10% difference from the ideal value). On the other hand, the late diastolic indices were not reliable, because the noise greatly deviated the values of these indices. We concluded that the 2nd and the 3rd-order harmonics of Fourier transform is considered to be optimum for curve fitting, and various systolic and early diastolic indices of global and regional curves can be evaluated by this technique.
PracticeClinical medicine
Keywordsgated blood pool imaging, Fourier transform, phase analysis, simulation study, higher order harmonics

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