| Japanese |
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| Title | フーリエ高次解析法を用いたマルチゲート心血液プール像の壁運動の定量評価 - (1) 虚血性心疾患への応用 - |
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| Subtitle | 原著 |
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| Authors | 玉木長良*, 向井孝夫*, 湊小太郎*, 林信成*, 藤田透*, 森田陸司*, 鳥塚莞爾*, 田巻俊一**, 鈴木幸園**, 野原隆司**, 門田和紀**, 神原啓文**, 河合忠一**, 石井靖*** |
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| Authors(kana) | |
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| Organization | *京都大学医学部放射線核医学科, **第三内科, ***福井医科大学放射線科 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 3 |
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| Page | 289-300 |
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| Year/Month | 1983/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 RIマルチゲート心血液プール像より得た, 左室全体および画素ごとの容量曲線をフーリエ高次項にて近似した. これより左室の駆出率 (EF), 収縮末期までの時間 (TES), 最大駆出速度 (PER), PERまでの時間 (TPE), 最大充満速度 (PFR), PFRまでの時間 (TPF) を算出した. またおのおのの機能図より, 3つの位相の広がり [TES (SD), TPE (SD), TPF (SD)]を得た. さらには左室を8区分してそれぞれの位相も求めた. 以上の指標を元に, 心筋梗塞10例を含む虚血性心疾患22例と健常人8例を対象として, 左室壁運動の定量的評価を行った. PFRは最も良く両者を分離し, sensitivity 91%, specificity 100%であった. 次いでPER (64%, 88%), TPF (SD) (68%, 88%) も良い診断精度を示した. 各位相分布の広がりは, 心筋梗塞群で有意に高値を示し, asynchrony の存在が示された. フーリエ高次近似法は, 曲線近似の精度を高め, 収縮期と拡張期の指標を分離して描出できる方法として, 虚血性心疾患の評価に有用であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | gated blood-pool, phase analysis, higher-order harmonics, coronary artery disease, cardiac function |
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| English |
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| Title | Quantitation of Regional and Global Cardiac Performance by Phase Analysis Using Higher-order Harmonics - (1) Evaluation of Coronary Artery Disease - |
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| Subtitle | Original Articles |
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| Authors | Nagara TAMAKI*, Takao MUKAI*, Kotaro MINATO*, Nobushige HAYASHI*, Toru FUJITA*, Rikushi MORITA*, Kanji TORIZUKA*, Shunichi TAMAKI**, Yukinoso SUZUKI**, Ryuji NOHARA**, Kazunori KADOTA**, Hirofumi KAMBARA**, Chuichi KAWAI**, Yasushi ISHII*** |
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| Authors(kana) | |
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| Organization | *,**Kyoto University Medical School, ***Department of Radiology, Fukui Medical School |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 3 |
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| Page | 289-300 |
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| Year/Month | 1983/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A new Fourier analysis of gated blood-pool images using higher order harmonics has been investigated in order to perform more accurate curve fitting and to evaluate diastolic function separately from systolic function. Thirty cases including 8 normal persons (N), 12 patients with coronary artery disease without evidence of infarction (CAD 1) and 10 patients with infarction (CAD 2) were examined. From the higher frequency fitted single pixel and global time-activity curves, six parameters were calculated amplitude (EF), phase (TES), peak ejection rate (PER), time to PER (TPE), peak filling rate (PFR) and time to PFR (TPF). PER and PFR were significantly lower in CAD 1 (3.67 + 0.63 and 1.85 + 0.47 EDV/sec, respectively) and CAD 2 (2.47 + 0.37 and 1.85 + 0.47 EDV/sec, respectively) than in N (3.73 + 0.47 and 3.20 + 0.35 EDV/sec, respectively). TES, TPE and TPF were higher in CAD 1 (424 + 46, 223 + 34 and 153 + 40 msec, respectively) than in N (367 + 48, 174 + 33 and 124 + 17 msec, respectively). Each phase image (TES, TPE and TPF) and its histogram were genetared. Temporal distribution (SD) of these histograms was higher in CAD 2 (TES (SD) : 16.5 + 13, TPE (SD) : 17.7 + 12.2, TPF (SD) 20.7 + 11.9 degree) than in N (5.5 + 1.6, 6.1 + 1.4 and 6.0 + 1.9 degree, respectively) indicating presence of asynchrony. We conclude that high frequency Fourier analysis, yielding better curve fitting and separate quantification of systolic and diastolic functions, is a valuable technique in evaluation of coronary artery disease. |
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| Practice | Clinical medicine |
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| Keywords | gated blood-pool, phase analysis, higher-order harmonics, coronary artery disease, cardiac function |
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