Japanese
TitleThallium-201心筋灌流シンチグラフィによる右室負荷の定量的評価の検討
Subtitle原著
Authors渡辺俊也*, 都田裕之*, 小池斌碩*, 板津英孝*, 河合直樹**, 外畑厳**
Authors(kana)
Organization*国立名古屋病院内科, **名古屋大学医学部第一内科
Journal核医学
Volume20
Number2
Page179-191
Year/Month1983/3
Article原著
Publisher日本核医学会
Abstract「要旨」201Tl心筋灌流シンチグラフィによる右室負荷の定量的評価の有用性検討を目的とし, 右室の圧および容量負荷群における本法と右心カテーテル検査の成績を比較検討した. 圧負荷群における右室収縮期圧および右室 - 左室仕事量比, 容量負荷群における肺 - 体血流比, 右室 - 左室仕事量比および右室収縮期圧はそれぞれ右室 - 左室壁201Tl摂取比または右室壁201Tl摂取率との間に有意の正相関を示した. 以上より, 本法は右室の圧および容量負荷の定量的評価に有用と結論された. また, 両右室負荷群の判別はtransitional view angleおよび右室 - 左室径比によりある程度可能であった. 本法を用いた心手術例の検討において, 圧負荷群では術後1か月で右室 - 左室壁201Tl摂取比は有意に減少したが, 右室壁201Tl摂取率は術後1年でも有意な減少を示さなかった. 一方, 容量負荷群では術後1か月で右室 - 左室壁201Tl摂取比のみならず右室壁201Tl摂取率も有意の減少を示した.
Practice臨床医学：一般
KeywordsRight ventricular pressure overload, Right ventricular volume overload, Transitional view angle, Right to left ventricular wall thallium-201 uptake ratio, Right ventricular wall to background thallium-201 uptake ratio
English
TitleQuantitative Evaluation of Right Ventricular Overload with Thallium-201 Myocardial Perfusion Scintigraphy
SubtitleOriginal Articles
AuthorsToshiya WATANABE, Hiroyuki MIYAKODA, Yoshihiro KOIKE, Hidetaka ITATSU, Naoki KAWAI*, Iwao SOTOBATA*
Authors(kana)
OrganizationDepartment of Internal Medicine, Nagoya National Hospital, *First Department of Internal Medicine, Nagoya University School of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume20
Number2
Page179-191
Year/Month1983/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] To study the clinical usefulness of quantitative evaluation of right ventricular overload with thallium-201 myocardial perfusion scintigraphy, the scintigraphy and right-heart catheterization were performed on patients with right ventricular pressure overload (RVPO) or right ventricular volume overload (RVVO). In 18 patients with RVPO, right ventricular systolic pressure correlated significantly both with the RV/LV wall thallium-201 uptake ratios (r=0.54, p<0.02) and the RV wall/background thallium-201 uptake ratios (r=0.70, p<0.01). RV/LV work ratios also significantly correlated with RV/LV wall thallium-201 uptake ratios (r=0.57, p<0.02). In 19 patients with RVVO, Qp/Qs and RV/LV work ratios both significantly correlated with RV/LV wall thallium-201 uptake ratios (r=0.78 and 0.87, respectively; p<0.001 for both) and RV wall/background thallium-201 uptake ratios (r=0.69, p<0.01 for both parameters). Right ventricular systolic pressure also correlated with RV/LV wall thallium-201 uptake ratios (r=0.57, p<0.02). Feasibility of the differentiation between RVPO and RVVO was suggested with use of "transitional view angle" and RV/LV diameter ratios obtained from the scintigram. In patients who underwent cardiac surgery, post-operative alleviations of the right ventricular overload were evaluated by the scintigraphy. There was a significant decrease in RV/LV wall thallium-201 uptake ratios, but no significant decrease in RV wall/background thallium-201 uptake ratios in patients with RVPO. On the other hand, there was a significant decrease both in RV/LV wall thallium-201 uptake ratios and RV wall/background thallium-201 uptake ratios in patients with RVVO. No significant changes were observed between the scintigraphic measurements obtained 1 month and 1 year after the surgery, irrespective of the type of right ventricular overloading. In conclusion, the thallium-201 myocardial perfusion scintigraphy can serve as a non-invasive means for quantitative evaluation of patients with right ventricular pressure or volume overloading.
PracticeClinical medicine
KeywordsRight ventricular pressure overload, Right ventricular volume overload, Transitional view angle, Right to left ventricular wall thallium-201 uptake ratio, Right ventricular wall to background thallium-201 uptake ratio

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