| Japanese |
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| Title | 骨シンチグラフィーによる肺癌骨転移の検討 |
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| Subtitle | 原著 |
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| Authors | 中野俊一*, 長谷川義尚*, 梶田明義**, 中村慎一郎***, 宝来威***, 池上晴道***, 松田実***, 岡本信洋****, 鍋島秀雄****, 土井修****, 小松原良雄*****, 石上重行*** |
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| Authors(kana) | |
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| Organization | *大阪府立成人病センターアイソトープ診療科, **放射線診断科, ***内科, ****外科, *****整形外科 |
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| Journal | 核医学 |
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| Volume | 20 |
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| Number | 1 |
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| Page | 37-43 |
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| Year/Month | 1983/2 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」肺癌148例に248回の骨スキャンを行い, 44例 (29.7%) に骨転移がみられた. 治療前の肺癌69例中骨転移を認めたのは12例 (17.4%) であるが, 骨スキャン施行前に決めた臨床病期がI, IIおよびIIIであった58例中6例 (10.3%) において骨スキャンにより骨転移が検出されて病期IVに改められ, 骨スキャンが臨床病期の決定に役立つことを明らかにした. 治療前の骨スキャンが陰性で, 追跡検査した48例中8例において (このうち7例では治療後16か月以内に) その後の骨スキャンで骨転移が検出された. このうち2例ではX線検査では明らかでなく骨穿刺細胞診などで転移が確認された. すなわち肺癌の治療開始後1〜2年以内に骨スキャンで骨転移の検出されることが多い. その他, 骨スキャンで骨転移の検出された症例の予後, 骨転移部位の分布などについても検討した. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone scintigraphy, Lung cancer, Staging, Follow-up |
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| English |
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| Title | Clinical Studies on the Detection of Bone Metastasis in Lung Cancer by Bone Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Syunichi NAKANO*, Yoshihisa HASEGAWA*, Akiyoshi KAJITA**, Shinichiro NAKAMURA***, Takeshi HORAI***, Harumichi IKEGAMI***, Minoru MATUDA***, Nobuhiro OKAMOTO****, Hideo NABESHIMA****, Osamu DOI****, Yoshio KOMATUBARA*****, Shigeyuki ISHIGAMI*** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine, **Department of Radiology, ***Department of Internal Medicine, ****Department of Surgery, *****Department of Orthopedics, The Center for Adult Diseases |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 20 |
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| Number | 1 |
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| Page | 37-43 |
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| Year/Month | 1983/2 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] The purpose of this study is to evaluate the clinical usefulness of bone scan to detect bone metastasis in lung cancer. Two hundred and forty-eight scans were performed on 148 patients using Tc-99m EHDP or Tc-99m MDP. Out of 74 patients with abnormal accumulations, 44 were attributed to bone metastasis, 23 to non-tumor conditions on bone, and 7 were suspected of bone metastasis but could not be confirmed. The bone metastasis was detected in 12 (17.4%) of 69 patients who were scanned before therapy, and in 15 (37.5%) of 40 patients who died within 2 months after bone scan. Among 58 patients whose clinical stage was classified as I, II, and III before bone scan, 6 were found to be in stage IV due to their positive scan. Forty-eight patients whose scans before therapy were negative, were followed up with the scan. During the course 8 cases turned positive, and in 7 of them the interval from the first negative to positive scan was shorter than 16 months. Two of them showed no abnormal findings on X-ray survey but one revealed metastasis by aspiration cytological examination of bone and the other by follow-up X-ray surveys. Out of 43 patients who were detected bone metastasis with bone scan, 28 died within 6 months and the additional 11 died within a year after the detection. In conclusion, the bone scan is found to be useful to decide the initial clinical stage of the patients with lung cancer, to predict their prognosis and to follow-up them. |
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| Practice | Clinical medicine |
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| Keywords | Bone scintigraphy, Lung cancer, Staging, Follow-up |
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