| Japanese |
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| Title | 原発性肺癌における 67Ga, 201Tl スキャンの臨床的検討 |
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| Subtitle | 短報 |
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| Authors | 戸川貴史*, 森谷浩史*, 木田利之***, 星野俊明**, 加藤寿**, 米本人生*, 星宏治*, 村岡英夫**, 木村和衛* |
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| Authors(kana) | |
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| Organization | *福島県立医科大学放射線科, **福島県立医科大学附属病院がん診療部, ***日本電々公社福島健康管理所 |
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| Journal | 核医学 |
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| Volume | 19 |
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| Number | 7 |
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| Page | 1045-1049 |
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| Year/Month | 1982/8 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」 67Ga-citrate, 201Tl-chlorideはいずれも腫瘍親和性核種として原発性肺癌の診断にも用いられているが, 肺癌における 201Tl スキャンの有用性は67Gaに比べ劣るとされている. 67Gaの肺癌への親和性は組織型とその分化度にも何らかの関連があるとされており, 201Tl においても同様の機序が考えられる. 著者らは22例の原発性肺癌に67Ga, 201Tl スキャンを併用したところ, 67Gaよりもむしろ 201Tl において病巣が強く陽性描画されたものが3例認められた. 67Ga, 201Tl をそれぞれ単独で肺癌の存在診断として用いるのみではなく, 両スキャン所見の相違が肺癌の組織型, 分化度を推定するための情報となり得るか否かその関連性を明らかにするため若干の検討を加えた. 「II. 対象および方法」 手術, 経気管支的肺生検などにより組織型が確定した原発性肺癌22例 (腺癌7例, 扁平上皮癌6例, 大細胞癌5例, 小細胞癌4例) を対象とした. |
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| Practice | 臨床医学：一般 |
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| Keywords | Primary lung cancer, 67Ga-citrate, 201Tl-chloride, Histologic type |
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| English |
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| Title | Clinical Evaluation of 67Ga and 201Tl Scans in Primary Lung Cancer |
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| Authors | Takashi TOGAWA*, Hiroshi MORIYA*, Toshiyuki KIDA***, Toshiaki HOSHINO**, Hisashi KATO**, Hitomi YONEMOTO*, Koji HOSHI*, Hideo MURAOKA**, Kazue KIMURA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Fukushima Medical College, **Cancer Clinic of Fukusima Medical College Hospital, ***Fukushima Health Administration Center, Nippon Telegraph and Telephone Public Co. |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 19 |
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| Number | 7 |
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| Page | 1045-1049 |
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| Year/Month | 1982/8 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 67Ga-citrate and 201Tl-chloride scans were perfomed on 22 patients with primary lung cancer (7 adenocarcinoma, 6 squamous cell carcinoma, 5 large cell carcinoma, 4 small cell carcinoma) and the findings were evaluated for different histologic types. The positive ratio of each scan was noted as follows : adenocarcinoma, 85.7% on 67Ga, 100% on 201Tl ; squamous cell carcinoma, 100% on 67Ga, 83.3% on 201Tl ; large cell carcinoma 60% on each scan ; small cell carcinoma, 100% on each scan. When the positive ratios of 67Ga and 201Tl scans were compared with histologic types, 67Ga was higher in squamous cell carcinoma but 201Tl was higher in adenocarcinoma. We defined lung cancer as 67Ga-predominant when the abnormal focus of activity at the lesion was more definite on 67Ga than 201Tl and as 201Tl-predominant when it was more definite on 201Tl. Fourteen cases of 22 were 67Ga-predominant, but three were 201Tl-predominant. All 6 cases of squmous cell carcinoma were 67Ga-predominant. Of 7 cases of adenocarcinoma, three were 67Ga-predominant but 2 were 201Tl-predominant. The affinity of 67Ga and 201Tl for lung cancer seems to have some relations with its histologic type, and its degree of differentiation. |
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| Practice | Clinical medicine |
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| Keywords | Primary lung cancer, 67Ga-citrate, 201Tl-chloride, Histologic type |
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