Japanese
Title123I-hippuranによる腎機能評価
Subtitle原著
Authors宍戸文男*, 舘野之男*, 福士清*, 入江俊章*, 岩田錬*, 玉手和彦**, 鈴木和年**, 中山隆**, 山崎統四郎*, 松本徹*, 村上優子***, 池平博夫****, 栗栖明***
Authors(kana)
Organization*放射線医学総合研究所臨床研究部, **技術部, ***病院部, ****山梨医科大学医学部
Journal核医学
Volume19
Number7
Page1001-1011
Year/Month1982/8
Article原著
Publisher日本核医学会
Abstract「要旨」 123I-hippuranを合成し, 腎盂尿路系の排泄障害が疑われる症例を主に腎シンチグラフィを行った. 得られた経時的なデータに基づき, 動態イメージ, 減算処理による腎実質イメージ, 局所レノグラム, 機能イメージを作成し, 従来から行われているレノグラムと比較し, その臨床的有用性について検討を加えた. 動態イメージでは腎の形態とその機能をイメージとして知ることが可能であった. 局所レノグラムではこれまで鑑別が困難であった腎実質と腎盂尿路系の機能を区別して知ることが可能であった. また, 機能イメージは局所レノグラムを1枚のイメージに要約したものとして重要な臨床情報になりうると考えられた. 以上のように123I-hippuranによる経時的腎シンチグラムデータを用いて行うこの検査方法は臨床上腎機能評価に有用と考えられた.
Practice臨床医学:一般
Keywordsregional kidney function, I-123-hippuran, dynamic image, functional image, regional renogram
English
TitleRegional Kidney Function Assessment with 123I-hippuran
SubtitleOriginal Articles
AuthorsFumio SHISHIDO*, Yukio TATENO*, Kiyoshi FUKUSHI*, Toshiaki IRIE*, Ren IWATA*, Kazuhiko TAMATE**, Kazutoshi SUZUKI**, Takashi NAKAYAMA**, Toshiro YAMASAKI*, Toru MATSUMOTO*, Yuko MURAKAMI***, Hiroo IKEHIRA****, Akira KURISU***
Authors(kana)
Organization*Division of Clinical Research, **Cyclotron Section, ***Hospital, National Institute of Radiological Sciences, ****Medical University of Yamanashi
JournalThe Japanese Journal of nuclear medicine
Volume19
Number7
Page1001-1011
Year/Month1982/8
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Serial renal scintigraphy using I-123-orthoiodohippurate (I-123-hippuran) was performed in cases who had been suspected of abnormality in renal function. Iodine-123 of high purity was produced by the cyclotron in our institute, and I-123-hippuran was synthesized by melting method. Dynamic renal images, subtracted renoparenchmal images, regional renograms, and functional renal images were processed from serial scintigraphic data after intravenous injection of about 2 mCi of I-123-hippuran, and were compared with the time-activity curve constructed for entire kidney. Serial dynamic renal images with 3 minutes intervals were indicated the morphological informations of shapes and sizes of kidneys. Regional renograms on renal parenchyma and pelvis were useful for distinguish from each function, and renal functional images were also important for assessment of regional function, as condenced into one picture. We conclude that these images and timeactivity curves processed from dynamic renal scintigraphy with I-123-hippuran provide a useful method to assess renal regional function.
PracticeClinical medicine
Keywordsregional kidney function, I-123-hippuran, dynamic image, functional image, regional renogram

【全文PDF】