| Japanese |
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| Title | 肝シンチグラムデータのコンピュータ処理による有効肝容積率の算出 |
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| Subtitle | 原著 |
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| Authors | 平野忠則*, 中川毅*, 前田寿登*, 荒木昭信**, 北野外紀雄**, 田口光雄*, 野口孝***, 川原田嘉文***, 水本龍二*** |
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| Authors(kana) | |
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| Organization | *三重大学医学部放射線科, **三重大学医学部附属病院中央放射線部, ***三重大学医学部第一外科 |
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| Journal | 核医学 |
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| Volume | 19 |
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| Number | 6 |
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| Page | 891-901 |
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| Year/Month | 1982/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」198Auコロイド, 99mTcコロイド, 131I-BSP等による肝シンチグラフィのデータをコンピュータで処理することにより, 局所肝機能を判定する指標として有効肝容積率を求める方法を考案した. すなわち, 前後両面の検出器から収集したデータにおいて, 対応する単位領域上の計数率の相乗平均を求め, 指定する領域について合計した. この方法によりγ線の吸収の計数率に及ぼす影響が簡便に, 近似的に補正され, 相乗平均の合計が線源の容積にほぼ比例する値となることを理論的に検討し, 種々のファントム実験で確認した. 臨床応用に際しては切除(または残存)領域を種々に想定してROIを設定し, 残存肝領域内の相乗平均の合計と全肝領域内の合計との比から有効肝容積率を求め, これに全肝機能予備力を反映するICG Rmaxを乗じて残存肝Rmaxを求めた. 79例の肝切除患者の成績において, 残存肝Rmaxが0.4mg/kg/min以上の65例ではいずれも経過良好であった. 本法により欠損像をともなったり, 不整な形態を示す肝に対しても正しく有効局所機能が測定され, 手術適応, 手術危険度の判定, 手術々式の選択に有用と思われた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Liver Scintigraphy, Liver Volume, Attenuation Correction. |
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| English |
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| Title | Estimation of Effective Liver Volume Rate by Processing Liver Scintigraphic Data with an On-line Computer |
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| Authors | Tadanori HIRANO*, Tsuyoshi NAKAGAWA*, Hisato MAEDA*, Akinobu ARAKI**, Tokio KITANO**, Mitsuo TAGUCHI*, Takashi NOGUCHI***, Yoshifumi KAWARADA***, Ryuji MIZUMOTO*** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Mie University School of Medicine, **Central Clinical Division of Radiology, Mie University Hospital, ***First Department of Surgery, Mie University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 19 |
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| Number | 6 |
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| Page | 891-901 |
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| Year/Month | 1982/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary]It is naturally important to estimate functional reserve of remnant liver tissue preoperatively at major hepatectomy. For this purpose a method is devised which can estimate regional liver function, refered to as effective liver volume rate (ELVR). The method is based on the regional counts on the liver scintigram with colloidal 198Au, colloidal 99mTc and/or 131I-BSP. Following the collection of scintigraphic data from anterior and posterior projection with a gamma camera and an on-line computer system, the geometric mean of the conjugate counts is automatically calculated for each of the elements over the 64×64 matrix and displayed on a CRT so that the brightness is proportional to the calculated values. Various regions of interest (ROI) are flagged on this image with a light pen or keys according to surgeon's operation plans. The ELVR is calculated as the proportion of the sum of the geometric means over the ROI to that over the whole liver area. Theoretically, the effect of attenuation can be approximately corrected by the geometric mean of the conjugate counts of which the accuracy is dependent on the energy of the gamma ray and body thickness. In a study with a 17.5 cm thick phantom, the geometric means were almost proportional to the volume of the source irrespective of the source-depth in the phantom with under-estimate of less than 5.3% with 198Au and 23% with 99mTc. Functional reserve was determined by the product of ELVR for the remnant liver portion by the ICG Rmax to obtain remnant ICG Rmax. It was evident from the data of 79 patients who had hepatectomy that postoperative course was favorable in 65 patients with remnant ICG Rmax of more than 0.4 mg/kg/min. This method was considered to be useful for the operation in determining the indication, selecting the operation method and estimating the risk. |
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| Practice | Clinical medicine |
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| Keywords | Liver Scintigraphy, Liver Volume, Attenuation Correction. |
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