| Japanese |
|---|
| Title | 放射線治療の骨シンチグラムに及ぼす影響について |
|---|
| Subtitle | 原著 |
|---|
| Authors | 角文明*, 中島哲夫*, 砂倉瑞良*, 石原明徳**, 佐々木康人***, 永井輝夫**** |
|---|
| Authors(kana) | |
|---|
| Organization | *埼玉県がんセンター放射線部(現在群馬県立ガンセンター麻酔科), **埼玉県立がんセンター病理部(現在三重大学医学部病理学教室), ***聖マリアンナ医科大学第三内科(現在東邦大学医学部放射線科教室), ****群馬大学医学部放射線科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 19 |
|---|
| Number | 5 |
|---|
| Page | 787-795 |
|---|
| Year/Month | 1982/6 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」骨スキャンは骨組織の局所機能を反映するもので, 局所機能の亢進した部位は陽性像として, 著しく低下した部位は欠損像としてみとめられる. 過去に胸椎か腰椎が照射野に含まれる放射線治療を受けた67例の99スキャンについて, 椎骨への放射能集積と照射から骨スキャン実施までの期間および受けた照射線量との関係を検討した. 照射線量が5,000rad以上でかつ照射終了後3か月以上経過した場合に高頻度に椎骨への放射能集積が減少した. このことから照射後の骨スキャンにみられる骨への放射能集積減少は照射がひきおこす後期反応に基づく骨の局所機能低下に由来すると考えられた. 67Gaクエン酸による腫瘍スキャンの放射能集積についても同様に検討したところ, 放射能集積は照射開始後早期に減少していることが多く, 1,000rad以下の低線量でもみとめられた. これは67Gaクエン酸が骨組織ではなく放射線感受性のより高い骨髄の造血系細胞により集積することを推論させた. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Bone Scan. Irradiation therapy 67Ga scan, cold bone lesion, 99mTc diphosphonate. |
|---|
| English |
|---|
| Title | The Effect of Radiation Therapy on Bone Scintigraphy |
|---|
| Subtitle | |
|---|
| Authors | Bunmei KADO*, Tetsuo NAKAJIMA*, Mizuyoshi SAKURA*, Akinori ISHIHARA**, Yasuhito SASAKI***, Teruo NAGAI**** |
|---|
| Authors(kana) | |
|---|
| Organization | *Devision of Radiology, Saitama Cancer Center, **Devision of Pathology, Saitama Cancer Center, ***Third Department of Internal Medicine, St. Marianna University School of Medicine, ****Department of Radiology, Gunma University School of Medicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 19 |
|---|
| Number | 5 |
|---|
| Page | 787-795 |
|---|
| Year/Month | 1982/6 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary]With the purpose to evaluate effect of radiation therapy on bone scintigraphy, ninety nine bone scans and Ga-67 citrate tumor scans performed on 67 patients, including 42 with cancer, 5 with esophageal cancer, 4 malignant lymphoma and 15 with other malignancy. The spinal uptake of Tc-99m diphosphonate and Ga-67 citrate were evaluated during or after radiation therapy involving thoracic and lumbar spines. The correlation among the spinal uptake of radioactivity in the radiation field, the irradiation dose and the interval after radiotherapy was investigated. The results revealed that 34 of 99 bone scans (34%) showed "decreased" radio-activity in the irradiated spines. Twenty six of 41 bone scans (63%) performed more than three months after radiotherapy showed "decreased" spinal uptake. Among the same 41 bone scans, 16 of 21 bone scans (76%) taken in patients who received more than 5000 rads showed "decreased" spinal uptake. The decreased spinal uptake was irreversible. Eight cases changed to "decreased" from "equilibrated" during follow up study after radiotherapy. Twenty two of 31 cases (71%) with Ga tumor scans, which were performed in the earlier periods and with less dose of radiotherapy as compared with bone scans, showed "decreased" spinal uptake, which suggests impaired Ga-67 uptake by the bone marrow rather than the spinal bone. The factors causing decreased uptake of radioactivity in bone scan after irradiation were discussed in view of irradiation effect on bone tissue. The descrepancy of uptake of radioactivity between bone scan and Ga tumor scan was also discussed reviewing difference of radiation effect on bone and bone marrow cells. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Bone Scan. Irradiation therapy 67Ga scan, cold bone lesion, 99mTc diphosphonate. |
|---|