Japanese
Titleマルチゲート法心プールデータについてのフーリエ解析応用による心functional imaging - 基礎的検討およびその応用について -
Subtitle原著
Authors前田寿登*, 竹田寛*, 中川毅*, 山口信夫*, 田口光雄*, 小西得司**
Authors(kana)
Organization*三重大学医学部放射線医学教室, **三重大学医学部第一内科学教室
Journal核医学
Volume19
Number5
Page765-776
Year/Month1982/6
Article原著
Publisher日本核医学会
Abstract「要旨」99mTc標識赤血球を用いた心マルチゲート・データの画素ごとの時間-放射能(T-A)データについてフーリエ解析を応用し, 高次周波項までを用いて近似された曲線から心収縮, 拡張期動態の評価に有用な指標を求め, これらを指標とするfunctional image(FI)を作成し, その基礎的検討を行った. 400心拍で収集されたデータに対してfilter factor 10.2のマップ・スムージングを行うことにより, 正常例での基本周波によるphase imageは左心域でほぼ均等で, 標準偏差(5例の平均値)11.8度ときわめて狭い良好な分布を示し得た. 心室の局所的収縮, 拡張動態の特性を描出するためには, 画素ごとのT-Aデータに対して第3次周波項までを利用する近似法が必要かつ十分であるという結果を得た. さらにこれから得られる9個の指標を用いての解析は, 最近多く試みられている基本周波の位相角, 振幅の両指標のみによるFIでは描出困難であったより詳細な心機能評価が可能であることを示した.
Practice臨床医学：一般
KeywordsFunctional imaging, Gated blood pool study, Fourier analysis, Data processing.
English
TitleA New Cardiac Functional Imaging by Application of Fourier Analysis to Gated Blood-pool Study. A Basic Investigation
Subtitle
AuthorsHisato MAEDA*, Kan TAKEDA*, Tsuyoshi NAKAGAWA*, Nobuo YAMAGUCHI*, Mitsuo TAGUCHI*, Tokuji KONISHI**
Authors(kana)
Organization*Department of Radiology **First Department of Internal Medicine, Mie University school of Medicine
JournalThe Japanese Journal of nuclear medicine
Volume19
Number5
Page765-776
Year/Month1982/6
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary]A new cardiac functional imaging was developed, using not only the fundamental but also the higher harmonic components of regional time-activity curves. After blood-pool equilibration of 15-20 mCi Tc-99m red blood cells, labeled in vivo, 28-frame gated images in 64×64 matrix form were acquiered with the GCA-401-5 gamma camera in the modified left anterior oblique projection and stored in the GMS-90 computer system. A time-activity curve of each pixel was approximated by the sum for terms up to the 3rd frequency of its Fourier series. To evaluate the ventricular systolic and diastolic performances, nine parameters were analyzed from thus fitted curve and displayed on a colour CRT in a 64×64 matrix form. Considering difficulties of patients due to prolonged examination time and accidental errors due to statistical fluctuation, 400 beat-acquisition of data and map smoothing for the data with a filter factor of 10.2 were thought to be most preferable. On the basis of these data preparations, temporal Fourier analysis was applied to the processing. The synthesis of the regional time-activity curve with the harmonic components up to the 3rd frequency was considered to be most reasonable because of the least aberration due to statistical fluctuation and close agreement between the global original LV time-activity data and the regional fitted curves for the normal subjects. In patients with cardiomyopathy, the detailed informations on the regional ventricular systolic and diastolic performances could be detected by this new functional imaging of the heart, which were unable to obtain from the images using the fundamental harmonic only. We conclude that the new imaging method is superior for assessing the regional cardiac performances.
PracticeClinical medicine
KeywordsFunctional imaging, Gated blood pool study, Fourier analysis, Data processing.

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