Japanese
Title腎細胞癌における99mTc - DMSA腎, 99mTc - MDP骨, 67Ga - citrate腫瘍シンチグラフィー, ことにGaシンチグラフィーの有用性の検討
Subtitle原著
Authors川村寿一*, 伊藤坦*, 吉田修*, 藤田透**, 福永仁夫**, 森田陸司**, 鳥塚莞爾**
Authors(kana)
Organization*京都大学医学部泌尿器科学教室, **京都大学医学部核医学科教室
Journal核医学
Volume19
Number3
Page357-368
Year/Month1982/4
Article原著
Publisher日本核医学会
Abstract「要旨」腎細胞癌15例について, 99mTc-DMSA腎シンチグラム, 99mTc-MDP骨シンチグラム, 67Ga-citrate腫瘍シンチグラム上の患側腎所見を検討した. 1. 腎シンチグラム上, 初期でメージでDMSAの取込みがあり, 後期イメージで同所が欠損する腎細胞癌を疑う基準が12例に満たされた. 2. 骨シンチグラム上, 淡く描出されるか, 無描出のことが多かったが, 少数例に腫瘍周辺の拡張腎杯腎盂腔に排泄されたMDPの蓄積を認め, これが「hot spot」として描出された. 3. 腫瘍シンチグラム上, 10例に本腫瘍が「hot spot」として描出され, これら症例の臨床的特徴として, high stageで, 血液生化学上, 赤沈, CRPの亢進, 血清蛋白のα2globulin分画, 血清ferritinの増加があげられた. Ga腫瘍シンチグラムが本腫瘍の早期診断に有用かどうか断定はできないが, 進行期癌での予後推測や転移巣の発見には有用と思われた.
Practice臨床医学：一般
Keywords99m-Tc-DMSA renal scintigram, 99m-Tc-MDP bone scintigram, 67-Ga-citrate scintigram, renal cell carcinoma, Hot Spot.
English
TitleLocal Findings of Renal Cell Carcinoma on 99m - Tc - DMSA Renal, 99m - Tc - MDP Bone and 67 - Ga - Citrate Scintigraphies
Subtitle
AuthorsJuichi KAWAMURA*, Hitoshi ITOH*, Osamu YOSHIDA*, Toru FUJITA**, Masao FUKUNAGA**, Rikushi MORITA**, Kanji TORIZUKA**
Authors(kana)
Organization*Department of Urology, **Department of Nuclear Medicine, Faculty of Medicine, Kyoto University
JournalThe Japanese Journal of nuclear medicine
Volume19
Number3
Page357-368
Year/Month1982/4
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract99m-Tc-DMSA renal, 99m-Tc-MDP bone and 67-Ga-citrate scintigraphies were applied to the recent series of 15 patients with renal cell carcinoma. Immediately after the intravenous administration of 3.3 mCi of DMSA, the early image was taken and 3 hours later the late image taken, using a gamma scinticamera. The criteria for the cortical vascular lesions such as local uptake of DMSA in the early image and local defect in the late image met in 12patients. 20mCi of 99m-Tc-MDP was given intravenously and 3 hours later the whole body bone scintigram was taken, using the whole body scanner or the TM multiplane imager system(Pho/Con). Local defect and/or faint visualization in the diseased kidney were demonstrated in most patients. In a few patients was seen local MDP accumulation which corresponded to the MDP retention in the dilated pelvocalyceal system. 3mCi of 67-Ga-citrate was administered intravenously and 72 hours later the whole body image was taken, using the Pho/Con. Gallium accumulation in the diseased kidney was noticed as a "Hot Spot" in 10 patients, while the equivocal accumulation in 2 and no renal uptake in 3 patients. Gallium uptake in the diseased kidney correlates well with the clinicopathologically higher stage, elevations of erythrocyte sedimentation rate and CRP, or increased levels of alpha-2 glubulin in serum total protein and serum ferritin. The whole body investigation with gallium image gives us a clue to diagnosing a primary site of malignancy and evaluating prognosis in the case of renal cell carcinoma.
PracticeClinical medicine
Keywords99m-Tc-DMSA renal scintigram, 99m-Tc-MDP bone scintigram, 67-Ga-citrate scintigram, renal cell carcinoma, Hot Spot.

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