Japanese
Title負荷心RIアンジオグラフィに関する研究 (第1報) - 実際の方法に関する検討 -
Subtitle原著
Authors西村恒彦*, 斎藤宗靖**, 植原敏勇*, 小塚隆弘*
Authors(kana)
Organization*国立循環器病センター放診部, **内科
Journal核医学
Volume19
Number1
Page83-91
Year/Month1982/2
Article原著
Publisher日本核医学会
Abstract「要旨」負荷心RIアンジオグラフィにて虚血性心疾患症例における冠動脈病変の検出および心予備能の評価を試みた. とくに, 本稿では, 負荷心RIアンジオグラフィの実際の方法について検討した. 負荷心RIアンジオグラフィは, 99mTc in vivo RBC標識によるマルチゲート法とし臥位自転車エルコメータによる漸増負荷法とした. かつ高感度コリメータを用いることにより1〜2分間以内に負荷中のデータ収集が可能であった. なお負荷中における体位の固定のため肩当て, グリップ棒を考案, 心電図の記録は12誘導にてカーボン電極を使用した. この結果, 運動負荷時において5%以上LVEFが増加した群を正常, 5%以内の増加ないし減少を示す群を虚血心の反応とすると冠動脈病変の存在診断に対するsensitivity, specificityは, 冠動脈造影を施行している30症例(狭心症)にてそれぞれ, 83.3, 100%であった. しかし, 左心機能の反応が運動負荷量などに左右されること, 虚血性心疾患以外にも運動負荷時LVEFは低下する場合があること, LVEF, wall motionの精度についても考慮する必要があることから, 本法の適用にあたり精度高い方法論の確立とともにその成績は充分吟味して解釈する必要があると考えられる.
Practice臨床医学:一般
KeywordsExercise radionuclide ventriculography(ERV), Detection of CAD, Graded exercise method, LVEF(rest/exercise)
English
TitleDetection of Coronary Artery Disease by Exercise Radionuclide Ventriculography (1) Practical Consideration
Subtitle
AuthorsTsunehiko NISHIMURA*, Muneyasu SAITO**, Toshiisa UEHARA*, Takahiro KOZUKA*
Authors(kana)
OrganizationDepartment of Diagnostic Radiology and Cardiology, National Cardiovascular Center
JournalThe Japanese Journal of nuclear medicine
Volume19
Number1
Page83-91
Year/Month1982/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractIn order to assess the detection of coronary artery disease(CAD)and LV functional reserve, exercise radionuclide ventriculography(ERV)were performed in 80 patients who underwent selective cardiac catneterization for evaluation of chest pain syndrome. 70 patients had CAD(30 patients with angina pectoris and 40 patients with myocardial infarction)and 10 did not. In this study, to obtain accurate data by ERV, its practical consideration were metioned. Radionuclide cardioangiography with 99mTc-in vivo RBC labeling were performed using an Anger camera attached with high-sense collimator and on-line minicomputer system. For data aquisition, multi-gated method were used, especially during exercise, list mode collection was suitable for ERV because of variable R-R intervals. Patient stability was performed with an adjustable shoulder support and hand grip, ECG monitoring system by carbon electrolode was used to obtain during exercise. Exercise protocal was graded bicycle ergometer in supine position. As the results, in the patients of CAD, changes of LVEF from rest to exercise were under 5%, while in normal patients, LVEF increased over 5% in all patients. In 30 patients with angina pectoris, the ERV was abnormal in 25 for a sensitivity of 83.3% and specificity of 100%. The ERV were thought to be superior than stress ECG for the detection of CAD. In conclusion, with increasing clinical application, the use of ERV is rapidly becoming widerspread but the excellent results were thought to depend upon the careful attention to equipment and exercise procedure.
PracticeClinical medicine
KeywordsExercise radionuclide ventriculography(ERV), Detection of CAD, Graded exercise method, LVEF(rest/exercise)

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