Japanese
Title肝シンチグラムの臨床的有効度の定量的評価 - (1) 方法論とSOL診断のROC解析を中心に -
Subtitle原著
Authors松本徹*, 飯沼武*, 舘野之男*, 町田喜久雄**
Authors(kana)
Organization*放射線医学総合研究所, 臨床研究部, **東京大学医学部放射線科
Journal核医学
Volume19
Number1
Page51-65
Year/Month1982/2
Article原著
Publisher日本核医学会
Abstract「要旨」肝シンチグラムの臨床的有効度を客観的, 定量的に評価するため, 8施設から406例の診断確定症例をretrospectiveに収集し, 異った施設の肝シンチグラムを11人の医師が読影するという実験を行った. 各症例の臨床情報と医師による読影所見データは2種のワークシートに記録され, そのデータをもとに種々のROC解析が行われた. 本報ではまずこの実験で用いた方法の詳細が述べられる. つぎにその方法により得られた多くの知見の中から, SOL診断のROC解析に的をしぼり, その結果と方法論上のいくつかの問題点が示される.
Practice臨床医学：一般
KeywordsClinical efficacy No. 1, liver image, ROC analysis.
English
TitleEstimation of Clinical Efficacy for Scintigraphic Images of Liver (1) Methods and ROC Analysis for SOL - detection
Subtitle
AuthorsToru MATUMOTO*, Takeshi A. IINUMA*, Yukio TATENO*, Kikuo MACHIDA**
Authors(kana)
Organization*National Institute of Radiological Sciences, **Department of Radiology, Tokyo University
JournalThe Japanese Journal of nuclear medicine
Volume19
Number1
Page51-65
Year/Month1982/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractIn this study, the clinical efficacy No. 1(diagnostic accuracy)of liver images on various liver diseases is investigated. From 8 different medical institutions the liver images of 406 cases most of which were imaged with 99mTc-phytate and confirmed for its final diagnosis by the autopsy, surgery and other techniques excluding the liver scintigraphy were collected. In order to evaluate the results of image reading, an input sheet for computer was designed to describe the confirmed diagnosis of each case. The liver images were read by 11 physicians from the 8 institutions that presented the cases and the results of reading were recorded on the work sheet for computer input. The work sheet includes abnormality in shape, size and position of the liver, position and number of SOL, and diagnosis of liver diseases, etc. By comparing the record of confirmed diagnosis and the results of image reading for individual case, various programs of analysis are being undertaken. The accuracy in detecting the SOL by means of receiver operating characteristic(ROC)analysis is presented here. The results of analysis are as follows. (1)ROC curves are rather similar in all physicians and average ROC points are TPR=71, 80, 91%, FPR=5, 15, 27%, respectively. (2)The SOL of size larger than 3 cm are detected more easily than those of size less than 3 cm, although number of SOL less than 3 cm is only nine cases and so variation of TPR between physicians is large. It is found that the ROC curve for many SOL of small size is almost identical to that of SOL larger than 3 cm. As to the detection of SOL larger than 3 cm, Anger camera and scanner are found to have an identical capability.
PracticeClinical medicine
KeywordsClinical efficacy No. 1, liver image, ROC analysis.

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