Japanese
Title急性心筋梗塞患者におけるThallium - 201心筋シンチグラムの再分布像の検討 - 回復可能な虚血心筋の評価 -
Subtitle原著
Authors近藤真言*, 霜野幸雄*, 宮崎俊一*
Authors(kana)
Organization*市立島田市民病院循環器科
Journal核医学
Volume19
Number1
Page39-49
Year/Month1982/2
Article原著
Publisher日本核医学会
Abstract「要旨」心筋梗塞急性期でのThallium-201心筋シンチグラムの再分布像の評価から, 梗塞領域と周辺虚血領域との分離が識別可能かどうかを検討した. Tl-2011回注入5分後より初期分布像, 3〜4時間後に再分布像のイメージングを行った. 急性心筋梗塞患者7例に発症3日以内に検査を施行し, 5例に再分布を認めた. 生存した6例で慢性期に左室造影を行い壁運動異常の重症度と再分布の有無の対比を行った. 再分布領域は再分布しなかった領域に比べて明らかに壁運動異常は少なく, 両者の相関を認めた. そして, 剖検した1例で再分布領域の心外膜側にviableな心筋を病理学的に確認した. 以上より, Tl-2011回注入法による経時的イメージングは急性期での梗塞領域と周辺のreversibleな, と同時にjeopardized areaとして存在する虚血領域との識別にとって有用であり, かつ急性心筋梗塞早期におけるrevascularizationの適応をきめる一つの検査法となる可能性をもっていると考えられる
Practice臨床医学:一般
KeywordsAcute myocardial infarction, Thallium-201, Viable myocardium, Jeopardized area, Redistribution.
English
TitleAssessment of Reversibility of Ischemic Myocardium by Thallium - 201 Redistribution in Patients with Acute Myocardial Infarction
Subtitle
AuthorsMakoto KONDO, Yukio SHIMONO, Shunichi MIYAZAKI
Authors(kana)
OrganizationThe division of Cardiology, Shimada City Hospital
JournalThe Japanese Journal of nuclear medicine
Volume19
Number1
Page39-49
Year/Month1982/2
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
AbstractTo determine whether redistribution of thallium-201 scintigraphic defects of acute myocardial infarction(AMI)could be used to distinguish between ischemic and infarcted area, serial myocardial scintigrams after a single dose thallium-201 were obtained within 3 days after onset in 7 patients with AMI. Imaging began 5 minutes after the thallium injection and was repeated 3 to 4 hours later. All patients showed initial definite defects. Five patients demonstrated some redistribution to initial defects. One to 2 months after onset, left ventriculography was done in the 6 patients to compare redistribution with wall motion abnormality. Five segments with redistribution revealed normal or hypokinetic wall motion, whereas 10 of 13 segments without redistribution were akinetic or dyskinetic and 3 were hypokinetic. One case was autopsied in 8 days after thallium-201 study. In the region which showed the redistribution, viable myocardium was recognized in the epicardial layer, but the region which showed noredistribution was transmural infarction. These data suggest that redistribution in patients with AMI may provide a means to evaluate myocardial viability and may be useful to determine a indication of early myocardial revascularization.
PracticeClinical medicine
KeywordsAcute myocardial infarction, Thallium-201, Viable myocardium, Jeopardized area, Redistribution.

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