| Japanese |
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| Title | 81mKrによる右房, 右心機能に関する研究 - intervention studyへの応用 - |
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| Subtitle | 研究速報 |
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| Authors | 西村恒彦*, 植原敏勇*, 林田孝平*, 小塚隆弘* |
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| Authors(kana) | |
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| Organization | *国立循環器病センター放診部 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 10 |
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| Page | 1431-1436 |
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| Year/Month | 1981/12 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. 緒言」81mKrをボーラス注入法として用いることにより主として右心系の計測に応用する方法を開発した. しかも, 本核種が短半減期(13秒)であることを利用すれば, 繰返しファーストパス法を施行することができ, intervention studyにも有用である. 本論文では, 81mKrによる右房, 右心機能の評価として, (1)右心における急速流入効果による右室駆出分画(RVEF)の算出, (2)虚血心における運動負荷によるRVEFの変動, (3)三尖弁閉鎖不全における重症度の推定について若干の検討を行ったので報告する. 「II. 81mKr注入方法」81Rb-81mKrジェネレータ(日本メジフィジックス社製)を用いボーラス注入法とした. すなわち5%ブドウ糖液にて81mKrを溶出する際, ジェネレータの前後に2 ml, 20 mlのディスポーザブル注射筒を連結し, 81mKrを10 mCi/2 mlとして抽出し, 20mlの5%ブドウ糖液にてフラッシュすることによりボーラス注入が行える. |
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| Practice | 臨床医学：一般 |
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| Keywords | 123I-hippuran, Dynamic renal image, Regional renogram, Functional image |
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| English |
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| Title | Evaluation of right heart (RA, RV)cardiac function by short - lived radionuclide (81mKr) |
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| Subtitle | Rapid Communications |
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| Authors | Tsunehiko NISHIMURA*, Toshiisa UEHARA*, Kohei HAYASHIDA*, Takahiro KOZUKA* |
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| Authors(kana) | |
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| Organization | *Dept. of Radiology and Nuclear Medicine National Cardiovascular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 10 |
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| Page | 1431-1436 |
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| Year/Month | 1981/12 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | A short-lived radionuclide(81mKr)is potentially an ideal tracer for the determination of RVEF by repeated bolus injection without measuring left heart, lung, and background. We decided to evaluate 81mKr for RV, RA function; especially, for the application for intervention study. (1)Evaluation of rapid injection effects. The value of RVEF was calculated by repeat bolus injection of 81mKr in various speeds. RVEF was increased in the rapid injection, while decreased in the slow injection because of incomplete mixing of RI in the right ventricular chamber. (2)Evaluation of exercise RVEF in coronary artery disease(CAD). In CAD patients, RVEF from rest to exercise were not significantly decreased, while decline of RVEF indicated right ventricular MI with severe stenosis of right coronary artery. (3)Evaluation of degree of Tricuspid regurgitation(TR). In patients with valvular heart diseases suspected TR, the time activity curve of RA, RV by 81mKr was generated. The degree of TR by radionuclide method was good agreement with doppler and RV graphy. |
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| Practice | Clinical medicine |
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| Keywords | 123I-hippuran, Dynamic renal image, Regional renogram, Functional image |
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