| Japanese |
|---|
| Title | 111In-oxine標識白血球の膿瘍描出能 - 特にウサギにおける67Ga citrateとの比較 - |
|---|
| Subtitle | 原著 |
|---|
| Authors | 宇野公一*, 内山暁***, 今関恵子**, 三好武美**, 秋庭弘道**, 有水昇** |
|---|
| Authors(kana) | |
|---|
| Organization | *千葉大学医学部附属病院放射線部, **千葉大学医学部放射線科, ***山梨医科大学放射線医学教室 |
|---|
| Journal | 核医学 |
|---|
| Volume | 18 |
|---|
| Number | 10 |
|---|
| Page | 1413-1419 |
|---|
| Year/Month | 1981/12 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」テレピン油による膿瘍作製ウサギを用いて, 111In-oxine標識白血球による膿瘍描出を試み, またGe半導体検出器を用いて111In-oxine標識白血球と67Ga citrate同時投与による膿瘍描出能を比較検討した. アイソトープ投与後1時間, 24時間, 48時間のガンマカメラ像では, 48時間像が両核種とも最も良く膿瘍を描出できた. 111In-oxine標識白血球の体内分布は, 脾への放射能集積が最も多く, 肝, 腎, 膿瘍の順であった. 両核種投与後72時間で屠殺し, 膿瘍と健側筋肉とのg当りの投与量パーセント比は111Inが6.2に対し67Gaは7.6でやや67Gaの方が膿瘍への放射能集積は優るが, バックグラウンドが少なく像のきれいな111In-oxine標識白血球は軟部組織や下腹部の膿瘍描出には有効と考えられた. 白血球分離と標識操作に手間どるが, Specificityに乏しい67Ga citrateに変る炎症巣描出核種として今後期待される. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | 111In-oxine labeled leukocytes, Abscess imaging, 67Ga citrate, Ge semiconductor detector, Tissue distribution |
|---|
| English |
|---|
| Title | Abscess Imaging with 111In-oxine Labeled Leukocytes - A Comparison with 67Ga citrate in Rabbits Bearing Abscesses - |
|---|
| Subtitle | Original article |
|---|
| Authors | Kimiichi UNO*, Guio UCHIYAMA***, Keiko IMAZEKI**, Takeyoshi MIYOSHI**, Hiromichi AKIBA**, Noboru ARIMIZU** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, Chiba University Hospital, **Department of Radiology, Chiba University School of Medicine, ***Department of Radiology, Yamanashi University School of Modicine |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 18 |
|---|
| Number | 10 |
|---|
| Page | 1413-1419 |
|---|
| Year/Month | 1981/12 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | Abscess imaging with 111In-oxine labeled leukocytes was performed in rabbits bearing turpentine-induced abscesses. After simultaneus administration of 111In-oxine labeled leukocytes and 67Ga citrate, gamma camera images were obtained over a period of 48 hours. Rabbits were sacrificed 72 hours later and the radioactivities of rabbits' tissues were counted on using a germanium semiconductor detector. 111In-oxine labeled leukocytes showed almost the same abscess-to-muscle ratio as of 67Ga citrate. Delineated abscess images of 111In-oxine labeled leukocytes though, were superior to those of 67Ga citrate because of fairly low radioactivity in the body background. 111In-oxine labeled leukocytes imaging seems to be a useful procedure in detecting abscesses especially of lower abdomen and soft tissues. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | 111In-oxine labeled leukocytes, Abscess imaging, 67Ga citrate, Ge semiconductor detector, Tissue distribution |
|---|