Japanese
Title7-ピンホールコリメータによる心筋断層シンチグラフィー (第1報) - 心筋梗塞症例における有用性と限界について -
Subtitle原著
Authors西村恒彦*, 山田幸典*, 植原敏勇*, 林田孝平*, 香川雅昭*, 伊藤慎三*, 林真*, 小塚隆弘*
Authors(kana)
Organization*国立循環器病センター放診部
Journal核医学
Volume18
Number9
Page1271-1285
Year/Month1981/11
Article原著
Publisher日本核医学会
Abstract「要旨」 7-pinhole collimatorによる心筋断層シンチグラフィを導入, 心筋ファントム実験および臨床的検討を行った. 心筋ファントム実験はin vivo simulationによる手法を用い, 各断層面にてD/N比を求めたところ, 心尖部から遠ざかるにつれ分解能の低下および他の断層面との重なりのため本コリメータのtomographic powerの低下が梗塞診断に影響を与えることを示した. 次いで虚血性心疾患152症例を対象として従来法と比較した結果, 前壁, 下壁梗塞にて(H-RES, 7-PIN)のsensitivityはそれぞれ(88%, 96%)(66%, 91%)と7-pinhole collimatorの方が優れていた. しかし, specificityは(63%, 52%)と低下を示した. したがって, 本コリメータは単にシンチカメラに装着するのみで断層像を得られる利点はあるが, その臨床評価に際しては有用性とともに限界を熟知する必要があり, 本コリメータのみでは従来法を凌駕するものでなく, 相補なって用いることにより診断精度の向上が期待される.
Practice臨床医学:一般
Keywordsmyocardial perfusion imaging, sevenpinhole emission tomography, myocardial infarction, sensitivity/specificity, in vivo simulation of heart phantom
English
TitleValue and Limitation of Seven-pinhole Emission Tomography with Thallium-201 in Patients with Prior Myocardial Infarction
SubtitleOriginal Articles
AuthorsTsunehiko NISHIMURA, Yukinori YAMADA, Toshiisa UEHARA, Kohei HAYASHIDA, Masaaki KAGAWA, Shinzo ITO, Makoto HAYASHI, Takahiro KOZUKA
Authors(kana)
OrganizationDepartment of Radiology and Nuclear Medicine, National Cardiovascular Center
JournalThe Japanese Journal of nuclear medicine
Volume18
Number9
Page1271-1285
Year/Month1981/11
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Seven-pinhole emission tomography with thallium-201 has been studied in the patients with myocardial infarction and was compared with planner imaging. In this study, the sensitivity and specificity of the two approaches for the detection of prior myocardial infarction were compared. In 69 cases of anterior infarction, the sensitivity of tomographic and planner imaging was 88, 96%, while in 47 cases of inferior infarction, 61, 91% respectively. However, the specificity of tomographic and planner imaging was 50, 63%. And subendocardial infarction could not be detected by tomographic method. By basic and clinical studies, the seven-pinhole technique produced reconstructed images that offered a tomographic presentation of the object but did not quantitatively represent true cross sections of the object's activity distribution. The defect's activity concentration is not accurately reconstructed and it propagates longitudinally into some reconstructed planes that do not contain it because of the lack of tomographic power. In conclusion, the seven-pinhole tomographic approach has value and limitation in the detection of prior myocardial infarction, and seven-pinhole tomographic approach would be performed in addition to the conventional method.
PracticeClinical medicine
Keywordsmyocardial perfusion imaging, sevenpinhole emission tomography, myocardial infarction, sensitivity/specificity, in vivo simulation of heart phantom

【全文PDF】