| Japanese |
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| Title | 201Tl心筋摂取率測定の新しい試みとしての心筋/左室通過量 (H/S) 比の検討 |
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| Subtitle | 原著 |
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| Authors | 分校久志*, 中嶋憲一*, 利波紀久*, 久田欣一* |
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| Authors(kana) | |
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| Organization | *金沢大学医学部核医学教室 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 9 |
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| Page | 1263-1269 |
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| Year/Month | 1981/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 201Tl心筋uptake index算出の新しい方法として, 左室通過全201Tl量に対するuptake indexであるH/S比の算出を試み, 心/肝(H/L), 心/肺(H/P), 心/全投与量(H/T)の各uptak eindexおよびスキャンスコア, EFと対比検討した. H/Sは肺内201Tl摂取を除外する目的で左室での通過曲線より, 1/2の重みづけの肺バックグラウンド除去後, 指関数近似により求めた. H/Sは正常(5.95 +- 1.75(S.D.)), 非虚血性心疾患(4.79 +- 1.84(S.D.))で心筋梗塞(3.47 +- 1.18(S.D.))より有意に高値であった. (p < 0.1). H/SはH/P, EFと正の相関を, スコアと負の相関を認め, とくに梗塞例ではより高い相関(それぞれr = 0.71, 0.91, -0.95, p < 0.02, < 0.01, < 0.01)がみられたが, H/L, H/Tとは有意の相関は認めなかった. H/Sは左室平均通過時間と心筋量に影響される指標と考えられるが, 肺内201Tl摂取を除外できる点で有用な心筋血流の指標と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | 201Tl, uptake index, H/S ratio, ischemic heart disease. |
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| English |
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| Title | H/S Ratio as a New Index for Myocardial 201Tl Uptake |
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| Subtitle | Original Articles |
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| Authors | Hisashi BUNKO, Kenichi NAKAJIMA, Norihisa TONAMI, Kinichi HISADA |
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| Authors(kana) | |
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| Organization | Department of Nuclear Medicine, School of Medicine, Kanazawa University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 9 |
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| Page | 1263-1269 |
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| Year/Month | 1981/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In order to evaluate myocardial blood flow with 201T1, a new myocardial 201Tl uptake index "H/S ratio" is proposed. H/S ratio is derived from left ventricular first pass time activity curve by 1/2 weighted background subtraction and exponential curve fitting in order to exclude lung uptake of 201Tl. With this H/S ratio, myocardial uptake of 201Tl based upon total dose passing through left ventricle can be estimated. H/S ratio is calculated in 12 patients with old myocardial infarction(OMI), 8 with heart diseases without ischemia(HD)and 3 noncardiac patients (NHD). H/S is 5.95 +- 1.75(S.D.)for NHD, 4.79 +- 1.84(S.D.)for HD and 3.47 +- 1.18(S.D.)for OMI group. Difference is significant between OMI and the others(p, < 0.1). H/S correlates significantly with heart/lung(H/P)ratio, ejection fraction(EF)and multiplanar image score(p < 0.01). Especially in OMI group, these correlations are higher than in whole patients(r = 0.71, 0.91 and -0.95, respectively, p < 0.01). No correlation is seen between H/S and heart/total injected dose ratio, H/T) derived from Ishii's method(r = 0.03, p = NS). Theoretically, H/S is characterized by myocardial uptake of 201Tl divided by the product of total dose passing through the left ventricle and mean transit time of the left ventricle [H/(q0・t)] . Results of this study support this theoretical consideration. H/S is simple and useful myocardial 201Tl uptake index rather than H/T, because of excluding useless lung uptake of 201Tl. |
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| Practice | Clinical medicine |
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| Keywords | 201Tl, uptake index, H/S ratio, ischemic heart disease. |
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