| Japanese |
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| Title | 甲状腺結節患者における血中サイログロブリン値と甲状腺シンチグラムの有用性について |
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| Subtitle | 原著 |
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| Authors | 山下俊一*, 和泉元衛*, 三宅秀敏**, 中島彰久** |
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| Organization | *長崎大学医学部第一内科, **長崎大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 7 |
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| Page | 935-939 |
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| Year/Month | 1981/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 甲状腺結節患者の血中サイログロブリン(以下hTG)値を測定し, 同時に201Tl-chloride甲状腺シンチグラム(以下シンチ)を併用し各種結節の鑑別診断を試みた. 201Tlシンチで陽性像を示したものは分化型甲状腺癌(以下分化癌)14例中14例, 濾胞腺腫11例中11例, 腺腫様甲状腺腫5例中1例であった. 201Tlシンチで陰性像を示したものが腺腫様甲状腺腫5例中4例, 嚢胞9例中9例であった. 一方, hTGを測定したものでは転移のある分化癌18例ならびに濾胞腺腫12例で全例hTG高値を示した. しかし, 転移のない分化癌7例では1例をのぞき正常範囲であった. 以上の結果から, 甲状腺結節の鑑別方法として201Tlシンチを行ない陽性像であれば, (1)血中hTG値が正常ならば転移のない分化癌, (2)血中hTG値が上昇していれば転移のある分化癌か濾胞腺腫が考えられる. 201Tlシンチが陰性像なら血中hTG値の増加に関係なく腺腫様甲状腺腫か嚢胞である. |
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| Practice | 臨床医学：一般 |
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| Keywords | thyroglobulin, Tl-201 thyroid scintigraphy, thyroid nodule |
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| English |
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| Title | Clinical Evaluation of Measurement of Human Serum Thyroglobulin and Thyroid Scintigraphy for Differential Diagnosis of Thyroid Nodules |
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| Subtitle | Original Articles |
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| Authors | S. YAMASHITA*, M. IZUMI*, H. MIYAKE**, A. NAKASHIMA** |
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| Authors(kana) | |
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| Organization | *First Department of Internal Medicine, Nagasaki University School of Medicine, **Department of Radiology, Nagasaki University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 7 |
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| Page | 935-939 |
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| Year/Month | 1981/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] There is no good method for diagnostic evaluation of patients with thyroid nodules. The purpose of this study is to improve it by adopting combination of measurement of human serum thyroglobulin and thyroid scintigraphy. Human thyroglobulin(HTG)levels in sera from all the following patients were measured and both Tc-99m and Tl-201 thyroid scintigraphies were carried out for 14 of 25 patients with well differentiated thyroid cancer(TC), 11 of 12 with follicular adenoma(FA), 5 of 8 with adenomatous goiter(AG)and 9 of 16 with cyst(C). Both Tc-99m and Tl-201 scintigraphies of all patients with AG and C demonstrated cold nodules except one patient. On the other hand, all patients with TC and FA showed hot nodules by Tl-201 scintigraphy. It was found that HTG levels in sera from patients with FA and metastatic TC were elevated and that those from patients with non-metastatic TC were normal. These results suggest that thyroid nodules with both cold Tc-99m and Tl-201 scintigraphies are AG or C regardless of HTG levels in serum and that among thyroid nodules with hot Tl-201 scintigraphy, those with normal HTG levels in serum are non-metastatic TC and those with elevated HTG are FA or metastatic TC. |
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| Practice | Clinical medicine |
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| Keywords | thyroglobulin, Tl-201 thyroid scintigraphy, thyroid nodule |
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