Japanese
Title心RIアンジオグラフィによる右室駆出分画 (RVEF) の検討 - 第1報 RVEFの算出および急速流入効果について -
Subtitle原著
Authors植原敏勇*, 西村恒彦*, 内藤博昭*, 林田孝平*, 小塚隆弘*, 林真*, 香川雅昭*, 山田幸典*, 伊藤慎三*
Authors(kana)
Organization*国立循環器病センター放診部
Journal核医学
Volume18
Number7
Page917-927
Year/Month1981/8
Article原著
Publisher日本核医学会
Abstract「要旨」 心RIアンジオグラフィー・ファーストパス法を用いて, 独自の方法で右室駆出分画(RVEF)を算出した. 方法は(1)右室拡張末期(RVED)の像から右室収縮末期(RVES)の像をsubtractしてRVEDの輪郭を得, 右室の関心領域(ROI)とする. (2)この右室のROIの中に, 右室収縮期に右房が一部入りこむのを補正するため, 三尖弁上にROIを設定する. (3)BackgroundのROIを左上肺野に設定する. この3つのROIに関して時系列曲線を描き, (1)を(2), (3)で補正して心拍毎の駆出分画を算出し, 原則として4心拍の平均をRVEFとする. この際, RIの注入が速すぎると急速流入効果により右心室内のRI濃度が不均一になり, 逆に遅すぎると肺野に達したRIのBackgroundが大きくなり, RVEFの値がいずれも正確に求められない. 著者らは適度な速さのRI注入を心がけるとともに, 時系列曲線を補正してより正確なRVEFの値を得ている. 以上の方法について基礎的な検討を行ない, 臨床的に十分使用できるRVEF値を得られたと考えられた. 右室造影との相関は0.77である. 今後, 本法を用い各種心疾患の右心機能の臨床的評価を行なう予定である.
Practice臨床医学：一般
KeywordsRight ventricular ejection fraction. Radionuclide angiocardiography, Rapid infusion effect
English
TitleEvaluation of Right Ventricular Ejection Fraction by First-pass Radionuclide Angiocardiography
SubtitleOriginal Articles
AuthorsToshiisa UEHARA, Tsunehiko NISHIMURA, Kohei HAYASHIDA, Hiroaki NAITO, Takahiro KOZUKA, Makoto HAYASHI, Masaaki KAGAWA, Yukinori YAMADA, Shinzo ITOH
Authors(kana)
OrganizationDepartment of Radiology, National Cardiovascular Center
JournalThe Japanese Journal of nuclear medicine
Volume18
Number7
Page917-927
Year/Month1981/8
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Left ventricular ejection fraction(LVEF)obtained by radionuclide angiocardiography is a convenient and good parameter of the left ventricular function. Right ventricular ejection fraction(RVEF) also seems to be a good parameter of the right ventricular function. RVEF calculated from volumetry with contrast right ventriculography is not necessarily correct because of the complex figure of the right ventricle. On the other hand, the method of calculation of RVEF with radionuclide angiocardiography has the advantage of being able to ignore the complexity of figure of RV, because RI counts extracted from the timeactivity curve represent changes in ventricular volume. In this study, we developped an original method to calculate RVEF with first pass method. After setting of region of interest(ROI)of RV, background and ROI for correction of motion of tricuspid valve, we calculated RVEF with these time-activity curves. Since we found that too rapid infusion of RI made the time-activity curve of RV too steep, and too slow infusion of RI made the background of lung field too high, the appropriate infusion rate was required to get correct value of RVEF. In addition, the time-activity curve often became steep or flat in dependence of the speed of venous return and cardiac output of patients. In order to avoid the effect of infusion speed, the time-activity curve was fitted to linear curves and the value of RVEF was corrected. The validity of these methods was confirmed in our study. As the result, RVEF obtained with our methods appeared to have good correlation with that obtained from volumetry of contrast right ventriculography (r = 0.77)and to be very useful in clinical estimation of right ventricular function.
PracticeClinical medicine
KeywordsRight ventricular ejection fraction. Radionuclide angiocardiography, Rapid infusion effect

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