| Japanese |
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| Title | 骨シンチグラフィによる消化器癌骨転移の臨床的検討 |
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| Subtitle | 原著 |
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| Authors | 佛坂博正*, 藤村憲治** |
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| Organization | *熊本大学医学部放射線科, **国立熊本病院放射線科 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 5 |
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| Page | 591-599 |
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| Year/Month | 1981/6 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」消化器癌105例に, 99mTcリン酸化合物による骨シンチグラフィを行い, 32例 (30%) に骨転移がみられた. 原発臓器別骨転移率は, 食道癌14%(4/28) , 胃癌38% (12/32) , 大腸癌27% (6/22) , 肝癌67% (6/9) , 胆嚢と胆管癌14% (1/7) , 膵癌43% (3/7) であった. 一般に, 消化器癌は肝や肺に転移しやすいが, 骨転移は少ない. しかし, 著者らの結果では, 肝癌を除いた消化器癌骨転移陽性例26例のうち12例に肝や肺の転移はみられなかった. また肝癌骨転移例6例のうち2例に肺転移はみられなかった. そこで, 骨転移が疑われる時は, 肝や肺転移の有無にかかわらず骨シンチグラフィを行う必要がある. 特に大腸癌では脊椎静脈叢を介する骨転移が考えられるので, 積極的に検索すべきと思われる. 骨転移例の予後は悪く, 平均予後は約3.5か月であった. その他, 症状, アルカリフォスファターゼ, 骨X線写真所見, 消化器癌骨転移例の原発巣の組織像についても検討した. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone Scintigraphy, Bone Metastases, Carcinoma of the Digestive System |
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| English |
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| Title | Clinical Evaluation of Bone Metastases from Carcinoma of the Digestive System by Scintigraphy with 99mTc-phosphorous Compounds |
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| Subtitle | Original Articles |
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| Authors | Hiromasa BUSSAKA*, Noriharu FUJIMURA** |
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| Authors(kana) | |
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| Organization | *Department of Radiology, Kumamoto University Medical School, **Department of Radiology, National Kumamoto Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 5 |
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| Page | 591-599 |
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| Year/Month | 1981/6 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Bone scintigraphy with 99mTc-phosphorous compounds was performed on 105 patients with carcinoma of the digestive system. Thirty-two cases of them (30%) had bone metastases. These bone metastases were seen as follows : 14% (4/28) in carcinoma of the esophagus, 38% (12/32) in carcinoma of the stomach, 27% (6/22) in carcinoma of the colon, 67% (6/9) in carcinoma of the liver, 14% (1/7) in carcinoma of the gallbladder and bile duct, and 43% (3/7) in carcinoma of the pancreas respectively. Previous reports stated liver metastases were found frequently and early, lung metastases seldom and late, and bone metastases rarely. In our study, however, liver and lung metastases were not discovered in 12 cases with bone metastases from carcinoma of the esophagus, stomach, colon, gall-bladder, and pancreas. Two cases of carcinoma of the liver with bone metastases revealed no lung metastases. Therefore, if bone metastases were suspected, bone scintigraphy should be performed on patients with carcinoma of the digestive system with or without liver and lung metastases, especially on the cases with carcinoma of the colon because of the significance of the vertebral venous plexus as the metastatic route. Prognosis of the carcinoma of the digestive system with bone metastase was poor and average survival period was 3.5 months. Furthermore, symptoms, the results of alkaline phosphatase, roentgenographic findings, and histological findings of the primary focus of the digestive tract were discussed. |
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| Practice | Clinical medicine |
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| Keywords | Bone Scintigraphy, Bone Metastases, Carcinoma of the Digestive System |
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