| Japanese |
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| Title | in vivo標識99mTc-赤血球における標識率の検討 - RIアンジオグラフィにおける応用 - |
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| Subtitle | 原著 |
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| Authors | 林田孝平*, 西村恒彦*, 植原敏勇*, 小塚隆弘* |
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| Organization | *国立循環器病センター放射線診療部 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 4 |
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| Page | 495-501 |
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| Year/Month | 1981/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | <要旨> in vivo標識99mTc-赤血球によるRIアンジオグラフィ100例を施行し以下の結論を得た. 1)Sn-PYPと99mTcO4-の投与間隔は30分, 体重当りのSn(II)の投与量0.020mg/kgで, 赤血球標識率は96.67 ± 0.91%(n = 87)と高かった. (2)in vivo赤血球標識法とアルブミン標識法を全身のequilibrium imageで比較し, 前者は後者より, 鮮明で, イメージ効率の高い心・大血管プール像を得, 肝などのバックグラウンドが低かった. in vivo赤血球標識法でRI静注後5 〜 20分の血中カウントの変動率は, 1.67%とアルブミン標識法の7.07%に比し小さかった. (3)RIアンジオセット, RIインターミッテント21Gを用いてin vivo赤血球標識法によるRIアンジオグラフィが簡便に行なえるようになった. 本法は, 診断能の高い画像が得られるので, 心臓核医学への寄与は大きいと考えられる. |
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| Practice | 臨床医学：一般 |
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| Keywords | Labeling rate, In vivo RBC labeling, HSA labeling, Radionuclide angiography, RI ANGIOSET |
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| English |
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| Title | Studies on In Vivo Labeling Rate of Red Blood Cells with 99mTc-Pertechnetate in Radionuclide Angiography |
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| Subtitle | Original Articles |
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| Authors | Kohei HAYASHIDA, Tunehiko NISHIMURA, Toshiisa UEHARA, Takahiro KOZUKA |
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| Authors(kana) | |
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| Organization | Department of Diagnostic Radiology, National Cardiovaseular Center |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 4 |
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| Page | 495-501 |
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| Year/Month | 1981/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 100 cases of radionuclide angiography were performed by in vivo labeling of RBC(red blood cell)with 99mTc-pertechnetate. The labeling rate of RBC and the comparison between in vivo RBC labeling and HSA(human serum albumin)labeling were investigated. These conclusions are as follows : (1)The in vivo RBC labeling was done with two consecutive intravenous injections, first of Sn-PYP and then of 99mTc-pertechnetate. In this study, the labeling rate of RBC was 96.67 +- 0.91% with 0.020 mg/kg of Sn(II)and 30 minutes of time interval between two injections. (2)Comparing the whole body images between in vivo RBC labeling and HSA labeling, the method by in vivo RBC labeling revealed superior cardiovascular image than that by HSA labeling. After taking sequential blood samplings, the blood pool by in vivo RBC labeling was more stable than that by HSA labeling ; the rate of variation in counts was 1.67 and 7.07%, respectively, between 5 and 20 minutes after labeling. (3)RI ANGIOSET with RI INTERMITTENT 21G made up RBC labeling with 99mTcpertechnetate in vivo by only one procedure of intravenous injection. Radionuclide angiography by in vivo 99mTc-RBC labeling will be clinically beneficial to cardiovascular nuclear medicine. |
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| Practice | Clinical medicine |
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| Keywords | Labeling rate, In vivo RBC labeling, HSA labeling, Radionuclide angiography, RI ANGIOSET |
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