| Japanese |
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| Title | 骨病変に対する201Tl-chlorideシンチグラフィの臨床的価値について |
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| Subtitle | 原著 |
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| Authors | 宍戸文男*, 津屋旭**, 洪誠秀**, 徳元善昭**, 舘野之男*, 内田勲***, 川口智義****, 和田成仁****, 松本誠一****, 梅垣洋一郎** |
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| Authors(kana) | |
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| Organization | *放射線医学総合研究所臨床研究部, **癌研究会付属病院放射線科, ***癌研究会癌研究所物理研究部, ****癌研究会付属病院整形外科 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 4 |
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| Page | 455-462 |
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| Year/Month | 1981/5 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | <要旨> 201Tlと99mTc-MDPの2種類の放射性医薬品を使ってシンチグラフィを行った症例のうち診断の確定した例について, 検討を加えた. 骨病変の存在が確認された57例中, 201Tlでは43.9%に, 99mTc-MDPでは98.2%に異常所見が認められた. 原発性骨腫瘍で201Tlが陽性となった主な疾患は骨肉腫, 骨巨細胞腫であり, 201Tlの集積のみで悪性, 良性の鑑別を行うのは困難であった. 骨巨細胞腫の例では再発した病巣にも201Tlの集積が認められた. 転移性骨腫瘍では201Tlの有病正診率, 無病正診率は各々, 50%, 100%, 99mTc-MDPのそれらは各々, 100%, 54.2%であり, 99mTc-MDPを病巣の検出のために用い, その後201Tlの有無により, 骨転移か炎症かの判定に役立てるという利用法が可能と考えられた. 以上のように201Tlシンチグラフィを骨病変の診断に利用することは意義があると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone scintigraphy, 201Tl, 99mTc-MDP |
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| English |
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| Title | Clinical Evaluation of 201Tl-chloride Scintigraphy for Bone Lesions |
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| Subtitle | Original Articles |
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| Authors | Fumio SHISHIDO*, Akira TSUYA**, Seishu KO**, Yoshiaki TOKUMOTO**, Yukio TATENO*, Isao UCHIDA***, Tomoyoshi KAWAGUCHI****, Naruhito WADA****, Seiichi MATSUMOTO****, Yoichiro UMEGAKI** |
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| Authors(kana) | |
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| Organization | *Division of Clinical Research, National Institute of Radiological Sciences, **Department of Radiology, Cancer Institute Hospital, ***Department of Medical Physics, Cancer Institute, ****Department of Orthopedics, Cancer Institute Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 4 |
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| Page | 455-462 |
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| Year/Month | 1981/5 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Clinical evaluation of 201Tl-chloride scintigraphy for bone lesions was examined in 66 patients by Comparing with 99mTc-MDP scintigraphy. The abnormal accumulation of 201Tl was found in 43.9% of 57 patients with bone lesions, and that on 99mTc-MDP was 98.2%. The abnormal findings of 201Tl scintigraphy in cases with primary bone tumors were found in all cases with osteosarcomas and giant cell tumors. A case with recurrent giant cell tumor also had positive findings of 201Tl scanning. The sensitivity and specificity of 201Tl scanning for detecting bone metastases were 50% and 100%, and those of 99mTc-MDP scintigraphy were 100% and 54.2%, respectively. Positive images with 201Tl scintigraphy were obtained in several cases with metastatic bone tumors. In the cases with inflammatory bone diseases, no positive findings of 201Tl scanning were obtained, though in all of these cases 99mTc-MDP scintigraphic findings were positive. From these results, 201Tl scintigraphy for bone lesions is considered to be useful for the diagnosis of primary bone tumors and metastatic bone tumors. |
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| Practice | Clinical medicine |
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| Keywords | Bone scintigraphy, 201Tl, 99mTc-MDP |
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