| Japanese |
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| Title | 133Xe冠動脈内投与による局所心筋血流量の測定 - 201Tl心筋シンチグラムとの比較 - |
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| Subtitle | 原著 |
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| Authors | 米倉義晴*, 田巻俊一**, 向井孝夫*, 石井靖*, 玉木長良*, 本原征一郎**, 玉井秀男**, 上畠拓**, 尾藤慶三**, 安田隆三郎**, 芹生陽一**, 鳥塚莞爾* |
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| Authors(kana) | |
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| Organization | *京都大学医学部放射線核医学科, **滋賀県立成人病センター循環器科 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 3 |
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| Page | 293-301 |
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| Year/Month | 1981/4 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」不活性ガスの組織からの洗い出し過程より得られるspecific flowの測定は, 単位重量あたりの血流量を絶対値として求めることができる. 133Xeを冠動脈内に投与して, 各心筋局所について初期勾配法によりspecific flowを算出し, そのfunctional imageを作成した. これを201Tl心筋シンチグラム所見と対比し, 本法の臨床的意義について検討した. 正常群および冠動脈疾患群では両者の所見はほぼ一致したが, 心筋症群では15例中5例で201Tl心筋シンチグラムでは認められない局所血流の低下が133Xe法により認められた. すなわち201Tlによるシンチグラムでは, 心筋重量の増加が肥大心筋におけるわずかな血流低下を相殺してしまうことによると考えられた. この点で133Xe法は心筋重量の影響を受けないspecific flowとして検討しうる利点がある. しかしながら相重なる部位での不均一な血流成分を本法で明らかにするためには, 初期勾配法は充分でなく, 今後その解析法の工夫が必要と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | regional myocardial blood flow, coronary artery disease, cardiomyopathy, 133Xe, 201Tl myocardial perfusion imaging |
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| English |
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| Title | Measurement of Regional Myocardial Blood Flow by Intracoronary Arterial Injection of 133Xe - Comparison with 201Tl Myocardial Scintigraphy - |
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| Subtitle | Original Articles |
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| Authors | Yoshiharu YONEKURA*, Schunichi TAMAKI**, Takao MUKAI*, Yasushi ISHII*, Nagara TAMAKI*, Seiichiro MOTOHARA**, Hideo TAMAI**, Hiromu UEHATA**, Keizo BITO**, Ryuzaburo YASUDA**, Yoichi SERIU**, Kanji TORIZUKA* |
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| Authors(kana) | |
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| Organization | *Department of Radiology and Nuclear Medicine, Kyoto University School of Medicine, **Cardiovascular Division, Shiga Prefectural Medical Center for Adult Diseases |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 3 |
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| Page | 293-301 |
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| Year/Month | 1981/4 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] 201Tl myocardial perfusion imaging (MPI) has been estabilshed as a noninvasive method to evaluate myocardial blood flow distribution, which is a function of myocardial mass and blood flow. To measure the blood flow specifically, a washout process of 133Xe was analyzed to calculate the specific flow in each regional element, that is regional myocardial blood flow (RMBF). The RMBF was expressed in a form of spacial distribution, so-called functional image, and was compared with the 201Tl MPI. 30 cases including 5 with normal or mild coronary artery disease (CAD) (Group I), 10 with severe CAD (Group II) and 15 with hypertrophic or congestive cardiomyopathy (Group III) were studied. Following coronary angiography, 133Xe in saline solution was injected into the coronary artery and the washout process was imaged to be analyzed during initial 40 seconds in LAO 30° by a multicrystal gamma camera. RMBF in each regional element was calculated according to the initial slope method to be analyzed as the functional image' 201Tl MPI was also performed in RAO 30°, anterior, LAO 30°, LAO 45°, LAO 60° and left lateral position. Regional distribution of these two methods concerning myocardial perfusion were compared each other. These observed to be reasonable correlation between RMBF and MPI of Group I and Group II. However, in several cases of Group III, abnormal perfusion of hypertrophied mass was suggested to be persent in the RMBF image, which could not be resolved in 201Tl MPI but only hypertrophied mass was visualized. In conclusion, present type of imaging provided supplemental information to the conventional 201Tl MPI. |
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| Practice | Clinical medicine |
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| Keywords | regional myocardial blood flow, coronary artery disease, cardiomyopathy, 133Xe, 201Tl myocardial perfusion imaging |
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