| Japanese |
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| Title | 201Tl-chloride経直腸シンチグラフィによる門脈循環動態の診断 |
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| Subtitle | 研究速報 |
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| Authors | 利波紀久*, 中嶋憲一*, 道岸隆敏*, 松田博史*, 小泉潔*, 油野民雄*, 久田欣一*, 小林健一**, 服部信** |
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| Authors(kana) | |
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| Organization | *金沢大学医学部核医学科, **第一内科 |
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| Journal | 核医学 |
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| Volume | 18 |
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| Number | 2 |
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| Page | 205-209 |
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| Year/Month | 1981/3 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「I. はじめに」種々の肝疾患の病態を正確に把握するためには門脈系の循環動態の診断は極めて重要である. RIを用いたnon-invasiveな門脈循環動態診断法として経直腸法によるいくつかの報告があるが, 充分満足できる方法とは言えず広く普及するに至っていない. 著者らは201Tl-chlorideの新しい臨床応用を考案し発表してきているが, 一連の研究のなかで201Tlの局所集積の大部分は1回の還流によって決定し, それは局所血流と還流をうける細胞の摂取能力によって左右されることがわかっている. この201Tlのユニークな性質から, 201Tlを直腸内投与することによって門脈循環動態の診断に応用できることに気付き, 経直腸シンチグラフィとその解析を試みてきた. 従来の方法による経直腸シンチグラフィに比べ門脈大循環短絡の程度についての情報が容易に得られるため今後門脈循環動態の新しい診断法となりうると思われるので紹介する. |
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| Practice | 臨床医学：一般 |
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| Keywords | 201Tl-chloride, Per-rectal scintigraphy, portal circulation |
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| English |
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| Title | Evaluation of portal circulation by 201Tl-chloride Per-rectal scintigraphy |
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| Authors | Norihisa TONAMI*, Kenichi NAKAJIMA*, Takatoshi MICHIGISHI*, Hiroshi MATSUDA*, Kiyoshi KOIZUMI*, Tamio ABURANO*, Kinichi HISADA*, Kenichi KOBAYASHI**, Nobu HATTORI** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine and **First Department of Internal Medicine, Kanazawa University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 18 |
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| Number | 2 |
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| Page | 205-209 |
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| Year/Month | 1981/3 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Per-rectal scintigraphy using 201Tl-chloride was performed in 23 patients (normal 4, cirrhosis 13, chronic active hepatitis 3, acute hepatitis 1, others 2) . Two mCi of 201Tl-chloride was given rectally after emptying the rectum with the enema. Scintigrams were taken sequentially at 5 minutes interval up to 25 minutes with scintillation camera and time activity curves of the regions of interest over liver, heart, spleen and lung. The 20 minutes' heart/liver activity ratios were chosen to evaluate the degrees of porta-systemic collateral circulation. In patients without porta-systemic shunts, the liver was visualized in 0-5 minutes after administration, while other organs were obscure even in 20-25 minutes' image. In patients with portasystemic shunts the liver was not clearly visualized, while 201Tl appeared in the systemic circulation. Mean values+-SD of the 20 minutes' heart/liver activity ratios were 0.14+-0.07 in normal controls, 0.90+-0.26 in patients with cirrhosis and 0.18+-0.01 in patients with chronic active hepatitis respectively. The 20 minutes' heart/liver activity ratio seems to be essential to discriminate between normal or chronic active hepatitis and cirrhosis. This new perrectal scintigraphy using 201Tl-chloride is a noninvasive and useful method for evaluating the portal circulation. |
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| Practice | Clinical medicine |
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| Keywords | 201Tl-chloride, Per-rectal scintigraphy, portal circulation |
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