Japanese
Title放射性エロソール吸入肺シネシンチグラフィー序説
Subtitle原著
Authors井沢豊春*, 手島建夫*, 平野富男*, 蝦名昭男*, 今野淳*
Authors(kana)
Organization*東北大学抗酸菌病研究所内科
Journal核医学
Volume18
Number2
Page167-173
Year/Month1981/3
Article原著
Publisher日本核医学会
Abstract「要旨」非呼吸性肺機能の一つである肺における気道粘液線毛浄化機構研究の為の方法論として, 放射性エロソールを吸入させたのち, γ-カメラで連続計測を行ない, これを映画に編集して観察計測する方法を紹介し, これに放射性エロソール吸入肺シネシンチグラフィー (radioaerosol inhalation lung cine-scintigraphy) と名づけた. 本法は, 気道粘液線毛浄化機構の視覚的な動的観察のみならず, 正確な関心領域の設定を可能にし, 関心領域から得られたクリアランス曲線の合理的な解析を可能にする.
Practice臨床医学:一般
Keywordsradioaerosol, inhalation, cinescitigraphy, mucociliary clearance mechanism, clearance curve, non-respiratory lung function
English
TitleCine-scintigraphy of the Lungs Following Radioaerosol Inhalation An Introductory Report
SubtitleOriginal Articles
AuthorsToyoharu ISAWA, Takeo TESHIMA, Tomio HIRANO, Akio EBINA, Kiyoshi KONNO
Authors(kana)
OrganizationDepartment of Medicine, The Research Institute for Chest Diseases and Cancer, Tohoku University
JournalThe Japanese Journal of nuclear medicine
Volume18
Number2
Page167-173
Year/Month1981/3
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] A new modality of display following radioaerosol inhalation which we call "radioaerosol inhalation lung cine-scintigraphy" or "aerosol inhalation cine-scintigraphy" in short has enabled us to visualize the movement of inhaled radioactivity after its deposition in the lungs and allowed us to assess mucociliary clearance mechanism more directly and accurately than by any other means as far described. Mucociliary clearance is usually cephalad in direction from peripherally to proximally, but pathologic conditions such as pulmonary emphysema or bronchogenic carcinoma could not only retard or stop the clearance but also drive radioactivity transported from one lung into the opposite side or even retrogress the mucus flow. Radioaerosol inhalation lung cine-scintigraphy has also helped to select the regions of interest to get regional clearance curves and to interpret the meaning of each clearance curve thus obtained. This new modality is expected to serve as an indispensable means to study mucociliary clearance mechanism, a potentially important non-respiratory function of the lungs.
PracticeClinical medicine
Keywordsradioaerosol, inhalation, cinescitigraphy, mucociliary clearance mechanism, clearance curve, non-respiratory lung function

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