Japanese
Title川崎病 (MCLS) の67Ga-スキャン - 心臓障害診断の試み -
Subtitle短報
Authors伊藤和夫*, 斉藤知保子**, 永松一明***, 畑江泰子***
Authors(kana)
Organization*北海道大学医学部放射線科, **市立札幌病院放射線科, ***市立札幌病院小児科
Journal核医学
Volume18
Number1
Page81-86
Year/Month1981/1
Article報告
Publisher日本核医学会
Abstract「I. はじめに」 川崎病は, 乳幼児の皮膚, 粘膜, リンパ節を中心に多彩な臨床像を呈する疾患で, 詳細な臨床知見に基づき1967年川崎によって一つの症候群として報告された. この多彩な全身症状の特徴から臨床診断は比較的容易であり, また一見重篤感を伴う高熱や多彩な全身症状も副腎皮質ホルモン剤に良く反応し, 本症の多くは後遺症を残す事なく治癒する. しかし, 本症に心炎の合併する事が報告され, 冠動脈を中心にした動脈瘤と血栓形成による突然死が全罹患例の2%前後に存在する事が疫学調査で明らかにされてからは, 本症の治療と管理の面から心臓障害の有無を臨床的に把握する必要性が強く認識されるようになった. 本論文は, この川崎病に合併する心臓障害を診断する67Gaスキャンについて論じている.
Practice臨床医学:一般
KeywordsMCLS, 67Ga-scan, Myocardial Damage, Kawasaki's Disease
English
Title76Ga-citrate Scan for Evaluation of Myocardial Damage in Kawasaki's Disease (MCLS)
Subtitle
AuthorsKazuo ITOH*, Chihoko SAITO**, Ichimei NAGAMATSU***, Taiko HATAE***
Authors(kana)
Organization*Department of Radiology, Hokkaido University Hospital, **Department of Radiology, Sapporo City General Hospital, ***Department of Pediatrics, Sapporo City General Hospital
JournalThe Japanese Journal of nuclear medicine
Volume18
Number1
Page81-86
Year/Month1981/1
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Thirty one 67Ga scans were performed in twenty two cases with Kawasaki's disease (MCLS) . This study originated as a prospective study from an evaluation of myocardial damage in the MCLS which is critical in prognosis of this disease. The evaluation of 67Ga scan was followed to diagnostic criteria which were made with a degree of relative radioactive accumulation to the myocardial region at 48 hours of the postinjection. There were 6 cases (27.2%) as negative, 10 cases (45.6%) as equivocal and 6 cases (27.2%) as possible positive identified on 67Ga scan respectively. Two cases whithin 6 cases with possible positive scan showed clinical signs indicating myocardial damage. One was suddenly dead on twenty first day from a onset and in the other case was the coronary aneurysm disclosed on ultrasonography. The white blood cell count at scan is statistically defferent (p<0.05) between negative group and possible positive group on 67Ga scan. The mechanism of the accumulation of 67Ga-citrate to damaged myocardium can not be accurately explained. However, 67Ga might be appreciated to concentrate to an active pathological myocaridal process such as the diffuse myocarditis.
PracticeClinical medicine
KeywordsMCLS, 67Ga-scan, Myocardial Damage, Kawasaki's Disease

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