| Japanese |
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| Title | 99mTc-DTPAによる相対的分腎血流・機能の定量的評価 - 腎の大きさおよび計数密度との比較 - |
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| Subtitle | 《原著》 |
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| Authors | 瀬戸光*, 柿下正雄*, 二谷立介*, 利波紀久**, 久田欣一** |
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| Organization | *富山医科薬科大学医学部放射線医学教室, **金沢大学医学部核医学教室 |
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| Journal | 核医学 |
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| Volume | 17 |
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| Number | 7 |
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| Page | 799-808 |
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| Year/Month | 1980/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」99mTc-DTPAとコンピュータを接続したシンチレーションカメラを用いる簡便な相対的分腎血流・機能の定量的評価法を確立し, 種々の一側性腎疾患でその臨床的有用性について検討した. (1) 99mTc-DTPAと131I-Hippuranによる相対的分腎血流・機能指標は非常に良い相関を認めた(r=0.974). (2)健常腎症例(n=42)における相対的分腎血流・機能指標は左腎: 52.2±2.5%, 右腎: 47.8±2.5%であり, 性別では特に有意な差は認めなかった. (3)一側性腎尿路系疾患(n=28)および腎動脈狭窄症(n=5)においては, 患側腎の相対的分腎血流・機能指標ならびに相対的計数密度は健常腎に比べて有意に低値を示した(p<0.001). しかし, 腎の大きさでは腎動脈狭窄症の患側腎は有意に小さい値を示したが(p<0.001), 一側性腎尿路系疾患では有意な差は認めなかった. 以上のごとく, 本法は一側性腎疾患の早期診断および患側腎の機能状態の評価ならびに経過観察に有用であることがわかった. |
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| Practice | 臨床医学：一般 |
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| Keywords | 99mTc-DTPA, Separate kidney function, Quantitative evaluation |
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| English |
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| Title | Quantitative Evaluation of Relative Separate Renal Perfusion and Function with Tc-99m-DTPA : A Comparison with Renal Size and Count Density |
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| Subtitle | - Original Articles - |
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| Authors | Hikaru SETO*, Masao KAKISHITA*, Ryusuke FUTATSUYA*, Norihisa TONAMI**, Kinichi HISADA** |
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| Organization | *Department of Radiology, Faculty of Medicine, Toyama Medical and Pharmaceutical University, **Department of Nuclear Medicine, School of Medicine, Kanazawa University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 17 |
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| Number | 7 |
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| Page | 799-808 |
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| Year/Month | 1980/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] A new method of quantitative measurement of relative separate renal perfusion and function, using Tc-99m-DTPA and a scintillation camera interfaced to a computer was evaluated in various unilateral renal diseases. 1) Relative separate renal perfusion and function ratios with Tc-99m-DTPA were correlated well with I-131-Hippuran (r=0.974). 2) Normal values in the subjects with healthy Kidneys (n=42) were as follows; Left kidney: 52.2 +- 2.5%, Right kidney: 47.8 +- 2.5%.No significant difference was noted between sexes. 3) Relative separate renal perfusion and function ratios and count densities of the diseased kidneys in unilateral obstructive uropathy (n=28) and renal artery stenosis (n=5) were significantly decreased (p<0.001) in comparison with normal kidneys. Renal sizes of the diseased kidneys in renal artery stenosis were also significantly decreased (p<0.001). However, no significant decrease was noted in unilateral obstructive uropathy. This method is simple, atraumatic and of great clinical value to detect unilateral renal disease and to evaluate or follow-up the functioning state of the diseased kidney. |
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| Practice | Clinical medicine |
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| Keywords | 99mTc-DTPA, Separate kidney function, Quantitative evaluation |
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