| Japanese |
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| Title | 骨スキャン上欠損像を呈した骨病変 |
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| Subtitle | 原著 |
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| Authors | 角文明*, 中島哲夫*, 砂倉瑞良*, 石原明徳**, 佐々木康人***, 永井輝夫**** |
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| Authors(kana) | |
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| Organization | *埼玉県立がんセンター放射線部, **埼玉県立がんセンター病理部, ***聖マリアンナ医科大学第3内科, ****群馬大学医学部放射線科 |
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| Journal | 核医学 |
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| Volume | 17 |
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| Number | 6 |
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| Page | 655-664 |
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| Year/Month | 1980/7 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」 骨スキャンは従来, 放射能集積増加によって示される陽性像をもって異常所見とすることが多かった. しかし, 実際病巣があっても放射能集積に明らかな変化のないものや, 明らかな集積の欠損像を呈する場合も知られている. 骨スキャン上欠損像を呈した17例について, 原発病巣, 欠損発生部位, X線写真や腫瘍スキャンとの比較および病理組織所見との対比を検討した. 骨スキャン上の欠損像は扁平上皮癌の骨転移例に多くみられた. また, 欠損像は骨スキャンの特徴である病期の早いうちに出現するのではなく, 骨転移の進行した時点でみられることが多い. 骨スキャンを骨の局所機能の分布を示したものと考えると, 欠損像は局所機能の著しい低下を示す所見とみなすことができ, それは解剖学的要素である骨組織の量が著しく減少した場合にみとめられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone scan, 99mTc diphosphonate, cold bone lesion, metastatic bone tumor |
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| English |
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| Title | Cold Lesions Demonstrated on Bone Scintigraphy |
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| Subtitle | Original Articles |
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| Authors | Bunmei KADO*, Tetsuo NAKAJIMA*, Mizuyoshi SAKURA*, Akinori ISHIHARA**, Yasuhito SASAKI***, Teruo NAGAI**** |
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| Authors(kana) | |
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| Organization | *Devision of Radiology, Saitama Cancer Center, **Devision of Pathology, Saitama Cancer Center, ***Third Department of Internal Medicine, St. Marianna University School of Medicine, ****Department of Radiology, Gunma University School of Medicine |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 17 |
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| Number | 6 |
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| Page | 655-664 |
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| Year/Month | 1980/7 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Localized areas of decreased radioactivity in the bone were demonstrated in 17 cases (1.4%) of 1,213 bone scintigrams performed with Tc-99m diphosphonate. In 15 out of 17 cases "cold" bone lesions were found to be metastatic bone cancers. Primary sites of cancers included the lung (7 cases) , uterine cervix (3 cases) , thyroid (2 cases) , kidney (1 case) , prostata (1 case) and pancreas (1 case) . Other two lesions were found in primary site of chondroblastoma and metastatic site of osteosarcoma. Histological studies revealed squamous cell carcinoma in all 7 patients with lung cancer. Whereas "hot" bone lesions were found in 56% of adenocarcinoma and 31% of squamous cell carcinoma of the lung. High incidence of "cold" bone lesions were found in 3 (21%) out of 14 patients with cervical cancer who revealed positive bone scans. Abnormal bone scintigrams were found in 50 of 160 cases with breast cancer, but none of them showed "cold" bone lesions. In 14 cases increased uptake of radioactivity is noted around the cold lesions. Increased Ga-67 uptake in the "cold" lesion was found in 6 cases of lung cancer. Increased uptake of Tl-201 was found in the "cold" lesions in two patients with thyroid cancer. Postulated factors causing cold bone lesions were discussed reviewing literatures. |
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| Practice | Clinical medicine |
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| Keywords | Bone scan, 99mTc diphosphonate, cold bone lesion, metastatic bone tumor |
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