Japanese
Title骨シンチグラフィによる前立腺癌骨転移の臨床的検討
Subtitle原著
Authors佛坂博正*, 藤村憲治*, 山崎浩蔵**
Authors(kana)
Organization*熊本大学医学部放射線科, **熊本大学医学部泌尿器科
Journal核医学
Volume17
Number3
Page297-303
Year/Month1980/4
Article原著
Publisher日本核医学会
Abstract「要旨」25症例の前立腺癌に, 99mTcリン酸化合物を用いて骨シンチグラフィを行なった. 骨転移率は68% (17/25) で治療前と2週間以内の抗男性ホルモン療法後では検出率に差はなかった. 骨転移は腰椎, 骨盤, 肋骨に76% (13/17) , 胸椎に52% (9/25) と多く, 肋骨や頸椎, 胸骨さらには多発性およびび漫性骨転移の検出には骨X-Pよりも骨シンチグラフィが優れていた. 抗男性ホルモン療法後平均12か月で12症例に再シンチを行なった. 骨転移陽性例8例が平均10か月の期間で病巣の縮小やRI集積の低下がみられ, 症状, 骨X-P, 酸性ホスファターゼ, アルカリフォスファターゼの改善をみる例が多く, 治療効果判定の一所見になるかと思われた. 骨転移陰性例3例は平均19か月の期間で新しい骨転移は認められなかった. 骨シンチ時に得られる腎イメージは, 正常が64% (16/25) , 異常が36% (9/25) で左右非対称は16% (4/25) , 腎イメージのないものは20% (5/25) で, この5例は多発性およびび漫性骨転移症例であった.
Practice臨床医学:一般
KeywordsBone Scintigraphy, Carcinoma of the Prostate, 99mTc-phosphorous Compounds
English
TitleClinical Evaluation of Bone Metastases from Carcinoma of the Prostate by Bone Scintigraphy With 99mTc-phosphorous Compounds
SubtitleOriginal Articles
AuthorsHiromasa BUSSAKA*, Noriharu FUJIMURA*, Kozo YAMASAKI**
Authors(kana)
Organization*Department of Radiology, School of Medicine, Kumamoto University, **Department of Urology, School of Medicine, Kumamoto University
JournalThe Japanese Journal of nuclear medicine
Volume17
Number3
Page297-303
Year/Month1980/4
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] In 25 patients suffering from carcinoma of the prostate, bone scintigraphy using gamma camera was performed with 99mTc-phosphorous compounds. In 17 cases (68%) bone metastases were detected on the lumbar spine, pelvis, and ribs with the rate of 76% (13/17) and on the thoracic spine with 52% (9/25) . Bone scintigraphy was not only superior to radiographical examination with bone metastases of ribs, cervical spine and sternum, but also with multiple and diffuse bone metastases. In 12 cases, scintigraphical follow-up was carried out after hormone therapy for approximately 12 months. In 8 cases having bone metastases, regression on scintigram was seen after therapy for approximately 10 months, and also their symptoms, radiographical findings, acid phosphatase and alkaline phosphatase indicated better results. Scintigraphical regression could be thought as a criteria of response to treatment. Three cases without bone metastases remained negative after treatment for approximately 19 months. Sixteen cases (64%) of the bone scintigram showed normal results, and 9 cases (36%) abnormal. Four cases of these abnormal images were asymmetric and 5 cases were bilateral decreased renal uptake.
PracticeClinical medicine
KeywordsBone Scintigraphy, Carcinoma of the Prostate, 99mTc-phosphorous Compounds

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