| Japanese |
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| Title | RI心血管造影による虚血性心疾患における運動負荷時左心機能の検討 |
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| Subtitle | 短報 |
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| Authors | 栗原正*, 成田充啓*, 宇佐美暢久*, 瓦谷仁志*, 金尾啓右**, 本田稔**, 小川正** |
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| Organization | *住友病院内科, **住友病院アイソトープ室 |
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| Journal | 核医学 |
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| Volume | 17 |
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| Number | 2 |
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| Page | 205-209 |
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| Year/Month | 1980/2 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」健常3例, 虚血性心疾患11例に, 安静時および運動負荷時にRI心血管造影を施行し, cardiac performance reserveを検討した. 坐位で安静時および運動負荷時に, 末梢静脈より99mTcO4-をbolus注入することにより, 99mTcO4-の左室第1回通過時の心血管造影を得, これより, 左室駆出率および左室壁運動異常の運動負荷前後での変化をみた. 健常例では, 運動時に駆出率の向上をみた. 虚血性心疾患では, 運動負荷により, 安静時に存在したasynergyの増強または新たなasynergyの出現をみる例が多く, 駆出率は平均49.3±9.7%より42.5±10.2%へと低下した. 運動負荷RI心血管造影は, 虚血性心疾患のcardiac performance reserveの判定に有用であり, これらの患者の管理上有用であると考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Exercise stress, RI-angiocardiography, Left posterior oblique view, Left ventricular volume curve |
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| English |
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| Title | Assessment of Left Ventricular Function during Exercise in Ischemic Heart Disease by Radionuclide Angiocardiography |
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| Subtitle | Short Communication |
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| Authors | Tadashi KURIHARA, Michihiro NARITA, Masahisa USAMI, Hitoshi KAWARADANI, Keisuke KANAO, Minoru HONDA, Tadashi OGAWA |
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| Authors(kana) | |
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| Organization | Department of Internal Medicine and Division of Radioisotope, Sumitomo Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 17 |
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| Number | 2 |
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| Page | 205-209 |
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| Year/Month | 1980/2 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] : To evaluate cardiac performance reserve in patients with ischemic heart disease, radionuclide angiocardiography was performed at rest and during exercise in eleven patients with ischemic heart disease and three normal control subjects. Exercise radionuclide study was performed on a bicycle ergometer in a sitting position, with graded multistage exercise method, and when one of several endpoints developed, 20mCi of 99mTcO-4 was injected as a bolus, and first pass radionuclide angiocardiogram was obtained with computerized scintillation camera in left posterior oblique position. At rest, radionuclide angiocardiogram was obtained in a sitting, left posterior oblique position as during exercise. Data were acquired in list mode at ten millisecond intervals. 50 msec segments from R-wave of four to six consecutive beats at left heart peak radioactivity were summed to form left ventricular end-diastolic image, and left ventricular and background regions of interest were selected. Time activity curve from left ventricular region in one cardiac cycle was corrected by background activity, and left ventricular volume curve was made. Ejection fraction was computed with this volume curve. Regional wall motion studies were done with computor-generated end-diastolic and end-systolic perimeters. In all three normal controls, ejection fraction increased with exercise, and wall motion was normal at both states. While, in the majority of patients with ischemic heart disease, asynergy that was present at rest was worsened or new asynergy developed, and ejection fraction decreased from 49.3+-9.7% to 42.5+-10.2% with exercise. It was considered that cardiac performance reserve was depressed in the majority of patients with ischemic heart disease. In conclusion, radionuclide angiocardiography during exercise was useful in evaluating cardiac performance reserve in patients with ischemic heart disease, and was essential in the management of these patients. |
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| Practice | Clinical medicine |
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| Keywords | Exercise stress, RI-angiocardiography, Left posterior oblique view, Left ventricular volume curve |
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