| Japanese |
|---|
| Title | 子宮頸癌における血清CEA値およびフェリチン値の臨床応用 |
|---|
| Subtitle | 原著 |
|---|
| Authors | 伊東久夫*, 久保敦司*, 橋本省三*, 筒井章夫**, 栗原操寿** |
|---|
| Authors(kana) | |
|---|
| Organization | *慶応義塾大学医学部放射線医学教室, **慶応義塾大学医学部産婦人科学教室 |
|---|
| Journal | 核医学 |
|---|
| Volume | 17 |
|---|
| Number | 1 |
|---|
| Page | 1-7 |
|---|
| Year/Month | 1980/2 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」子宮頸癌患者の血清CEA値およびフェリチン値をradioimmunoassay法により定量した. CEA値は0〜I期の患者で9%, II〜IV期については50%に上昇を認めた. 血清フェリチン値はO〜I期で16%, II〜IV期では68%の患者に上昇がみられた. 子宮頸癌では血清フェリチン値の上昇を示す症例の方がCEA値の上昇例より多い. CEA値とフェリチン値を同時に測定すると, 一方又は両者の上昇している症例は, 0〜I期で23例中2例, II〜IV期は48例中39例であった. 手術標本を病理学的に検索した29例では, 子宮旁結合織への浸潤があった12例全例と, リンパ節転移のあった12例中11例に, 一方又は両者の値の上昇を認めた. 以上より, 血清フェリチン値とCEA値の同時定量は (1) 初期癌の検出に利用することは難しい ; (2) これらの値が上昇している症例はリンパ節転移や子宮旁結合織への浸潤が強く疑われる ; と考えられる. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Cervical cancer, serum CEA, serum Feritin, Radioimmunoassay |
|---|
| English |
|---|
| Title | Clinical Application of Serum CEA and Ferritin Levels in Cervical Cancer Patients |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Hisao ITO*, Atsushi KUBO*, Shozo HASHIMOTO*, Fumio TSUTSUI**, Soju KURIHARA** |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology, and **Department of Gynecology and Obstetrics, School of Medicine, Keio University |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 17 |
|---|
| Number | 1 |
|---|
| Page | 1-7 |
|---|
| Year/Month | 1980/2 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] : Serum CEA and ferritin levels were determined in patients with cervical cancer using the radioimmunoassay. Elevated CEA values were found in 9% of stage 0-I patients and 50% of stage II-IV. Elevated ferritin levels were also found in 16% of stage 0-I and 68% of stage II-IV. Determination of serum ferritin levels were more sensitive to detect cervical cancer than serum CEA. When serum CEA levels and ferritin levels were simultaneously determined, one of 13 patients with stage 0,1 of stage 10 with stage I, 20 of 28 steag II and 19 of 20 stage III had elevated CEA and/or ferritin levels. In 29 patients whose resected specimens were examined to certify the extension of the disease, all 12 patients with parametrial invasion and 10 of 11 with lymph node metastases had one or both of elevated levels. This result suggests that (1) determination of serum CEA and ferritin levels can not serve as a test for the diagnosis of early cervical cancer even if these two tests were perfomed simultaneously ; (2) an elevated serum CEA or ferritin level in patients with stage I and II indicates a greater likehood of parametrial invasion and/or lymph node metastasis. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Cervical cancer, serum CEA, serum Feritin, Radioimmunoassay |
|---|