Japanese |
Title | マルチゲート法を用いた心臓ペーシングにおける心機能の評価 |
Subtitle | 研究速報 |
Authors | 西村恒彦*, 小坂井嘉夫**, 鬼頭義次**, 藤田毅**, 小塚隆弘* |
Authors(kana) | |
Organization | *国立循環器病センター放診部, **国立循環器病センター心臓外科 |
Journal | 核医学 |
Volume | 16 |
Number | 8 |
Page | 1395-1400 |
Year/Month | 1979/11 |
Article | 報告 |
Publisher | 日本核医学会 |
Abstract | 「1. 緒言」Green, 飯尾らにより開発されたマルチゲート法によるRIアンジオグラフィは, 左室造影に比較して非観血的にくり返し左心機能を測定できる利点を有し, 薬剤, 運動負荷時の心機能の評価も試みられている. ところで, 完全房室ブロックなどを有する患者は, ペースメーカ治療によりペースメーカ植込み後, 終生にわたり心拍数の制御を受けることになり, 至適心拍数の設定, 種々の心拍数の変化による血行動態が問題となる. そこで, 本研究では, マルチゲート法の特性を利用して, レート可変型ペースメーカを植込んだ症例にて, 心臓ページング時における心拍数の変化による心機能の評価を試みたので報告する. 「2. 方法および対象」対象はレート可変型ペースメーカを植込んだ完全房室ブロックを有した4症例である. 99mTc-Albumin 15〜20mCi静注後, 平衡相にて高分解能コリメータを装着したシンチカメラ(Ohio-NuclearΣ410S型)とオンラインで接続したミニコンピュータ(DEC PDP 11/34 96KB)を用い, LAOにてマルチゲート法による心プールイメージングを行なった. |
Practice | 臨床医学:一般 |
Keywords | multi-gated method, dye method, left ventricular function, programmable pacemaker, ventricular pacing |
English |
Title | Fvaluationon of left ventricular Function at Programmable Pacemakers by Multi-gated Method |
Subtitle | Rapid Communication |
Authors | Tsunehiko NISHIMURA*, Yoshio KOSAKAI**, Yoshitsugu KITOH, Tsuyoshi FUJITA**, Takahiro KOZUKA* |
Authors(kana) | |
Organization | *Department of Cardiology, Nuclear Medicine and **Surgery National Cardiovascular Center |
Journal | The Japanese Journal of nuclear medicine |
Volume | 16 |
Number | 8 |
Page | 1395-1400 |
Year/Month | 1979/11 |
Article | Report |
Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
Abstract | [Summary] In recent year, with the development and use of programmable pacemakers, there has been a growing need for a method to measure the hemodynamic effects of changes in pacer parameters. In this study, multi-gated radionuclide angiography were applied to evaluate left ventricular function noninvasively in cardiac pacing at various heart rates. The parameters calculated from multi-gated and dye methods were cardiac output (CO), end diastolic volume (EDV), endsystolic volume (ESV), stroke volume (SV) and ejection fraction (EF). The relative SV counts determined from edge extraction of ED, ES images were good correlation with stroke volume by dye method. 4 patients of complete A-V block treated with programmable pacemaker were studied clinically at various heart rates (30-120/min) by these methods. According to the increase of herat rate, rate-output curve showed the flat type. EDV, ESV, SV were decreased gradually and EF was unvariable in all cases. In conclusion, left ventricular functions at ventricular pacing by increase of heart rate were mainly determined from the decrease of EDV caused by the shortening of filling time of left ventricle, therefore, other parameters were changed by the contractility of myocardium and Starling's law of cardiac function. |
Practice | Clinical medicine |
Keywords | multi-gated method, dye method, left ventricular function, programmable pacemaker, ventricular pacing |