| Japanese |
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| Title | Cardiac probeによる左室機能の解析 |
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| Subtitle | 原著 |
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| Authors | 中居賢司*, 飯尾正宏*, 村田啓*, 川口新一郎*, 外山比南子*, 千葉一夫*, 山田英夫*, 上田慶二** |
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| Authors(kana) | |
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| Organization | *東京都養育院附属病院核医学放射線部, **東京都養育院附属病院循環器科 |
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| Journal | 核医学 |
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| Volume | 16 |
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| Number | 8 |
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| Page | 1355-1363 |
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| Year/Month | 1979/11 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」Cardiac probe systemによる左室駆出分画の測定法を検討した. 本法は再現性が良く, 本法による駆出分画は, 心プールゲイト法による値と良い相関(r=0.93)を示した. この装置を用い, 冠動脈疾患群でIsometric handgrip exercise前後での駆出分画の評価を行なった. 負荷前後での駆出分画は, 正常群で55±11%から61±7.8%と増加をみたが, 冠動脈疾患群では, 61±3.2%から57±2.3%と減少した. 本法は, 非侵襲的で短時間での駆出分画の測定が可能であり, 負荷前後での駆出分画の測定により, 冠動脈疾患群の検出ができ, また, 各種心疾患の経過観察, 薬剤の効果判定などにも有用な検査法と考えられた. |
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| Practice | 臨床医学：一般 |
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| Keywords | Cardiac Probe System, First pass method, Equilibrium method, Left ventricular ejection fraction, Isometric handgrip exercise |
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| English |
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| Title | Analysis of Left Ventricular Function Using Cardiac Probe System |
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| Subtitle | Original Articles |
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| Authors | Kenji NAKAI*, Masahiro IIO*, Hajime MURATA*, Shin-ichiro KAWAGUCHI*, Hinako TOYAMA*, Kazuo CHIBA*, Hideo YAMADA*, Keiji UEDA** |
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| Authors(kana) | |
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| Organization | *Department of Nuclear Medicine & Radiological Science, **Division of Cardiology Department of Medicine, Tokyo Metropolitan Geriatric Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 16 |
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| Number | 8 |
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| Page | 1355-1363 |
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| Year/Month | 1979/11 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Measurement of ejection fraction by using Cardiac probe system was studied and compared. The first transit study, which was used dual detectorsystem, was designed as follows; the inner detector saw LV cavity and outer detector measured background activity. Immediately after the injection of 2 mCi of Tc-99m-HSA first transit study was performed at rest and during isometric hand grip exerise of 30% maximum voluntary contraction for 3 minutes. The difficulty with Cardiac probe measurement relates accurate contribution of background. Our computerized cardiac simulation demonstrated some differences between probe positioning. First pass and equilibrium analysis by Cardiac probe were compared with high temporal resolution gated method. There was a good correlation between these three techniques to obtain ejection fraction (γ=0.93, 0.86). And correlation between first pass and equilibrium analysis was good (γ=0.95). By this method all of 6 control cases showed increase in ejection fraction from 55+-11% at rest to 62+-8% at stress. Whereas all 4 cases of CAD showed decrease in ejection fraction from 60+-3% at rest to 57+-2% of stress. Equilibrium method provides us beat by beat analysis of LV function. The Carciac probe system could calculate ejection fraction without computor analysis and permits easy bed-side determination of serial EF in a 1-2 minutes, which was most useful during stress exercise. Isometric handgrip exercise is easily applied and safety administered stress. Therefore, Cardiac probe system made it possible to analysis global function of left ventricle of patient with CAD without any load on the patients and even under the physiological condition. |
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| Practice | Clinical medicine |
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| Keywords | Cardiac Probe System, First pass method, Equilibrium method, Left ventricular ejection fraction, Isometric handgrip exercise |
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