Japanese
Title99mTc-pertechnetate甲状腺RIアンギオグラフィーにおけるdiffuse hyperperfusionの臨床的意義
Subtitle原著
Authors分校久志*, 桑島章*, 利波紀久*, 久田欣一*
Authors(kana)
Organization*金沢大学医学部核医学教室
Journal核医学
Volume16
Number6
Page917-926
Year/Month1979/9
Article原著
Publisher日本核医学会
Abstract「要旨」99mTcO4-甲状腺RIアンギオグラフィーにおけるbilateral diffuse hyperperfusion (BDH) を示す例で, BDHの程度, 甲状腺腫の性状, 甲状腺機能, static image所見, 最終診断などと対比し, その臨床的意義について検討した. 143例の甲状腺RIアンギオグラフィー中, 不均一なBDHは腺腫様甲状腺腫の1例のみにみられ, 均一なBDHは42例にみられた. BDHの程度は甲状腺腫の性状, 甲状腺機能と相関を認めなかった. 均一なBDHを示す例は, 慢性甲状腺炎, 腺腫, 分化型腺癌, 甲状腺術後, Graves病, 正常例でみられたが, 結節性甲状腺腫では, 慢性甲状腺炎 (74.2%), 腺腫 (12.9%), 分化型腺癌 (6.5%), 甲状腺術後 (6.5%) にみられた. 結節性甲状腺腫でBDHを示しstatic imageで欠損 (-) では慢性甲状腺炎, 欠損 (+) では甲状腺腫瘍の可能性が高く, 有意義な所見であった (p<0.005). 甲状腺機能低下症でBDHを示す場合, および甲状腺機能に関係なく高度のBDHを示す場合は慢性甲状腺炎に特異的である (それぞれspecificity 100%, 94%).
Practice臨床医学：一般
KeywordsThyroid, RI-angiography, 99mTc-pertechnetate, diffuse hyperperfusion, nodular goiter
English
TitleClinical Evaluation of Diffuse Hyperperfusion in 99mTc-Pertechnetate Radionuclide Angiography of the Thyroid Gland
SubtitleOriginal Articles
AuthorsHisashi BUNKO, Akira KUWAJIMA, Norihisa TONAMI, Kinichi HISADA
Authors(kana)
OrganizationDepartment of Nuclear Medicine, School of Medicine, Kanazawa University
JournalThe Japanese Journal of nuclear medicine
Volume16
Number6
Page917-926
Year/Month1979/9
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] Patients with bilateral diffuse hyperperfusion (BDH) on 99mTc-pertechnetate (99mTcO4-) radionuclide angiography of the thyroid gland were comparede with other clinical informations (i.e. type of goiter, thyroid function, static image findings and final diagnosis) and evaluated its clinical significance. BDH was classified from grade (+-) to (++) according to activity within the gland compared with that in the common carotid artery at arterial phase. Out of 143 patients studied with radionuclide angiography of the thyroid gland, 1 patient showed marked and inhomogenous BDH and 42 patients showed homogenous BDH. Former had multinodular goiter which showed multiple cold nodules on static image, and was euthyroid adenomatous goiter. Among the 42 patients with homogenous BDH, no correlation was found between the grade of BDH and type of goiter (p>0.05) or thyroid function (p>0.01). Homogenous BDH was found among patients with chronic thyroiditis, adenoma, differentiated adenocarcinoma, thyroid surgery (enucleation of adenoma or cyst), Graves' disease or normal thyroid. Among the patients with nodular goiter, BDH was noted in the patients with chronic thyroiditis (74%), adenoma (13%), differentiated adenocarcinoma (7%) and thyroid surgery (7%). In the case of nodular goiter with BDH and homogenous radionuclide accumulation on static image (i.e. without cold nodule), the diagnosis of chronic thyroiditis was most likely, whereas nodular goiter with BDH and cold nodule, the diagnosis of thyroid neoplasms (adenoma or adenocarcinoma) was most likely (sensitivity ; 91% and 83%, specificity ; 63% and 92%, accuracy ; 84% and 90%, respectively, p<0.005). Although sensitivity and accuracy were low, both hypothyroid state with BDH and marked BDH regardless of thyroid function were specific for chronic thyroiditis (specificity ; 100% and 94%, respectively).
PracticeClinical medicine
KeywordsThyroid, RI-angiography, 99mTc-pertechnetate, diffuse hyperperfusion, nodular goiter

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