| Japanese |
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| Title | 201Tl-chlorideシンチグラフィによる甲状腺腫瘍の診断的価値 |
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| Subtitle | 原著 |
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| Authors | 千賀脩*, 宮川信*, 代田廣志*, 岩浅武彦*, 牧内正夫*, 降旗力男*, 矢野今朝人**, 宮沢正則**, 滝沢正臣** |
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| Organization | *信州大学医学部第2外科, **信州大学医学部附属病院中央放射線科 |
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| Journal | 核医学 |
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| Volume | 16 |
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| Number | 6 |
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| Page | 849-856 |
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| Year/Month | 1979/9 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」甲状腺疾患98例に201Tl-chlorideシンチグラフィを施行し, 組織診断の得られた82例のうち, とくに甲状腺腫瘍63例につき201Tl-chlorideの腫瘍内集積の有無, ならびに腫瘍組織内へのとりこみの程度を検討した. 1) 甲状腺癌では19例中15例 (78.9%) に腫瘍陽性像が認められた. また, 頸部ならびに縦隔の転移リンパ節にも, 主病巣と同程度の集積を認めた. 腫瘍陰性を示した癌は, 嚢胞を形成した乳頭腺癌と未分化癌であった. 2) 腺腫では, 40例中10例 (25%) に腫瘍陽性像が認められた. 組織型別にみると, 管状腺腫と索状腺腫は全例陽性像を示し, コロイド腺腫, 嚢腫は全例陰性像を示した. 以上の成績から, 201Tl-chlorideシンチグラフィは, 甲状腺腫瘍の良性, 悪性の鑑別には必ずしも役立たないが, 腺腫では比較的低分化なものに集積がみられ, 治療方針の決定に有力な情報を与えるものと考える. |
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| Practice | 臨床医学：一般 |
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| Keywords | 201Tl-chloride scintigraphy, Tumor affinity radioisotope, 67Ga-citrate scintigraphy |
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| English |
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| Title | Diagnostic Value of 201Tl-chloride Scintigraphy for Thyroid Tumors |
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| Subtitle | Original Articles |
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| Authors | Osamu SENGA*, Makoto MIYAKAWA*, Hiroshi SHIROTA*, Takehiko IWASA*, Masao MAKIUCHI*, Rikio FURIHATA*, Kesato YANO**, Masanori MIYAZAWA**, Masaomi TAKIZAWA** |
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| Authors(kana) | |
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| Organization | Department of Surgery, **Department of Radiology, School of Medicine, Shinshu University |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 16 |
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| Number | 6 |
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| Page | 849-856 |
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| Year/Month | 1979/9 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Among the 98 cases of thyroid disease on whom we performed 201Tl-chloride scintigraphy, we examined 82 cases which were given histological diagnosis. Of 19 cases of thyroid carcinoma, 15 cases were positive (78.9%). 3 cases among the 15 showed a strong accumulation in the metastatic lymph nodes of the neck and mediastinum. Of 40 cases of thyroid adenoma, 10 cases were positive (25%). In comparison, cases of hyperthyroidism and chronic thyroiditis were all positive and cases of subacute thyroiditis were all negative. The histological types of thyroid tumors were examined. Of 14 cases of papillary carcinoma, 12 cases were positive (85.7%). 2 cases of negative scanning showed almost complete cystic degeneration. 3 cases of follicular carcinoma were all positive, but 2 cases of anaplastic carcinoma were negative. With respect to adenomas, 7 cases of tubular adenoma and 3 cases of trabecular adenoma were all positive, but cases of colloid adenoma and thyroid cyst were all negative. As to the uptake ratio of 201Tl-chloride into the thyroid carcinoma and adenoma tissue, it was observed that papillary carcinoma absorbed 2.65 times as much as normal thyroid tissue, follicular carcinoma absorbed 5.82 times as much, tubular adenoma absorbed 5.45 times as much, trabecular adenoma absorbed 5.67 times as much, but colloid adenoma absorbed 1.65 times as much as normal thyroid tissue. From the above mentioned results, it was concluded that 201Tl-chloride has no specific affinity for malignant tumors and cannot be used to discriminate between carcinoma and adenoma, but the nodule which showed positive scanning by 201Tl-chloride must be indicated for surgery. |
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| Practice | Clinical medicine |
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| Keywords | 201Tl-chloride scintigraphy, Tumor affinity radioisotope, 67Ga-citrate scintigraphy |
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