Japanese
Title99mTc標識Bleomycinによる腫瘍シンチグラフィに関する研究 - 第2編 骨・軟部腫瘍における99mTc標識Bleomycin, 67Ga citrate, 99mTc燐酸化合物によるシンチグラフィと血管造影法との対比に関する研究 -
Subtitle原著
Authors小鳥輝男*
Authors(kana)
Organization*京都大学医学部附属病院放射線部
Journal核医学
Volume16
Number6
Page829-847
Year/Month1979/9
Article原著
Publisher日本核医学会
Abstract「要旨」悪性および良性の各種骨・軟部腫瘍患者に99mTc-Bleomycin (99mTc-BLM), 67Ga citrate (67Ga) による腫瘍シンチグラフィおよび99mTc燐酸化合物 (99mTc-PC) による骨シンチグラフィを行ない, さらに血管造影検査を行なって, これらの成績を比較検討した. 悪性骨・軟部腫瘍に対する99mTc-BLMシンチグラフィのsensitivity, specificityはそれぞれ, 87%, 68%であり, 67Gaによる67%, 43%に比し優れた成績を示した. また, 99mTc-BLMは悪性腫瘍の外部への浸潤病変をよく描出し, 特に若年性線維症の病変範囲の診断および治療後の経過観察に有用であった. 99mTc-PCによる骨シンチグラフィは骨新生の程度をよく反映し, また骨疾患の広がりをよく描出して, 99mTc-BLMと組み合わせることにより, 病変の性状と範囲の推定に有用であった. 血管造影法は術前検査として優れた手段であるのみならず, 骨・軟部病変の性状を正確に描出し, また, 99mTc-BLMと血管造影法とを組み合わせたsensitivity, specificityはそれぞれ100%, 88%と極めて高い値を示した.
Practice臨床医学:一般
KeywordsBone and Soft Tissue Tumor, 99mTc-BLM Scintigraphy, 67Ga Scintigraphy, Bone Scintigraphy, Angiography
English
TitleClinical Evaluation of Tumor Scintigraphy with 99mTc-Bleomycin. (Part II) Combined Studies of Tumor Scintigraphy with 99mTc-BLM and 67Ga-citrate, bone Scintigraphy and Angiography in Bone and Soft Tissue Tumors
SubtitleOriginal Articles
AuthorsTeruo ODORI
Authors(kana)
OrganizationDepartment of Radiology & Nuclear Medicine, Kyoto University Hospital
JournalThe Japanese Journal of nuclear medicine
Volume16
Number6
Page829-847
Year/Month1979/9
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] A comparative study with tumor scintigraphy using 99mTc-BLM and 67Ga-citrate (67Ga), bone scintigraphy and angiography was performed on various bone and soft tissue tumors. 99mTc-BLM was found to have an advantage over 67Ga in sensitivity and specifity for malignant tumors. 99mTc-BLM also well delineated the extent of the malignant lesions ; with particular usefullness in assessing the extent of the lesions of aggressive fibromatosis for the diagnosis and treatment. Bone scintigrams with phosphate compounds (99mTc-PC) delineated the bone lesions clearly, reflecting the increased bone reaction. The combined study with 99mTc-PC and 99mTc-BLM made it very easy to define the nature and the extent of the lesions. Angiography was found to be an excellent pre-operative means which delineated the extent of the lesions of bone and soft tissue and identify the nature. The combination study with 99mTc-BLM and angiography was proved to have the best sensivity (100%) and specifity (88%) in identifying the malignent tumors.
PracticeClinical medicine
KeywordsBone and Soft Tissue Tumor, 99mTc-BLM Scintigraphy, 67Ga Scintigraphy, Bone Scintigraphy, Angiography

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