| Japanese |
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| Title | 二核種同時測定による肝臓の減算シンチグラムの評価 |
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| Subtitle | 原著 |
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| Authors | 河合武司*, 前田裕子*, 小川翼*, 赤木弘昭* |
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| Organization | *大阪医科大学放射線医学教室 |
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| Journal | 核医学 |
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| Volume | 16 |
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| Number | 5 |
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| Page | 735-745 |
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| Year/Month | 1979/8 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」最近, 67Ga-citrateを用いた肝腫瘍を陽性に描画するシンチグラムが行なわれている. しかし67Ga-citrateは正常肝組織にも摂取され, 腸管内にも排泄されるので読影は必ずしも容易ではない. そのため67Ga-citrateと198Au-colloidを用い, 異時投与して, 二核種用波高分析器を装着したシンチカメラに中央演算処理装置を接続して同時測定を行い, 減算シンチグラム (67Ga像-198Au像) を作成した. 減算シンチグラムを行い診断の確定した133例を対象とした. 原発性肝癌22例 (16.5%) あり, 99mTc-colloidのシンチグラムで18例 (81.8%), 減算シンチグラムで22例 (100%) の病巣が検出できた. 肝硬変症は28例 (21.1%) あり, 99mTc-colloidのシンチグラムでSpace Occupying Lesionを認めた14例 (50.0%) 中, 全例を減算シンチグラムで腫瘍を否定し得た. 減算シンチグラムは, 肝臓癌の診断, 特に肝硬変症, 肝腫大との鑑別に有効であった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Subtraction scintigram, Double isotope, Liver tumor |
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| English |
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| Title | Evaluation of the Subtraction Scintigram in Simultaneous Study of the Double Isotope |
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| Subtitle | Original Articles |
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| Authors | Takeshi KAWAI, Hiroko MAEDA, Yoku OGAWA, Hiroaki AKAGI |
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| Authors(kana) | |
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| Organization | Department of Radiology, Osaka Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 16 |
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| Number | 5 |
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| Page | 735-745 |
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| Year/Month | 1979/8 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] In this report, double isotope method (subtraction scintigram) with Ga-67-citrate and Au-198-colloid was evaluated on liver scintigram, and clinical results were described. Two mCi of Ga-67-citrate (three days before the examination) and 300 μCi of Au-198-colloid were injected intravenously. Immediately after the injection of Au-198-colloid, data were collected by a gamma camera with two discriminaters (Nuclear-Chicago PHO/Gamma HP 6406 type), and by a central processing unit (Nova 1200 16 Kwds with moving head disk 4047, Diablo 31, graphic computer terminal 4002A, Tektronix, hardcopy unit 4601, Tektronix, and magnetic tape recorder TMZ). Recorded data were transfered to magnetic tape for the later use, and the computer processed subtraction scintigram (GA-67-citrate image subtracted by Au-198-colloid) and the lesions were displayed on CRT. The 161 cases (11.2%) in 1442 examinations with Tc-99m-colloid scintigrams were studied with double isotope method. The 133 (32.6%) in 161 cases had final diagnosis by autopsy, angiogram and clinical examination and were the subject of this study. In 18 cases (81.8%) of 22 cases with primary liver cancer and in 15 cases (83.3%) of 18 cases with metastatic liver cancer, space occupying lesions (S.O.L) were found with Tc-99m-colloid scintigrams, but the 22 cases (100%) of the former and the 13 cases (72.2%) of the later showed positive findings with subtraction scintigrams (Ga-Au). In 14 cases (50.0%) of the 28 cases with liver cirrhosis, S.O.L. was found with Tc-99m-colloid scintigram but the all cases were negated malignancy by subtraction scintigram. This results showed that subtraction scintigram was very helpful in differentiating malignant tumors from benign lesions and useful in liver scintigram. |
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| Practice | Clinical medicine |
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| Keywords | Subtraction scintigram, Double isotope, Liver tumor |
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