| Japanese |
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| Title | 99mTcによる血球標識にかんする研究 (第5報) - 99mTc標識赤血球によるRI心血管造影, とくにIn VitroおよびIn Vivo標識法の比較について - |
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| Subtitle | 短報 |
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| Authors | 内田立身*, 待井一男*, 大和田憲司*, 舟山進*, 池田精宏*, 小野和男*, 木田利之**, 刈米重夫* |
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| Authors(kana) | |
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| Organization | *福島県立医科大学第1内科, **福島県立医科大学放射線科 |
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| Journal | 核医学 |
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| Volume | 16 |
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| Number | 4 |
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| Page | 563-567 |
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| Year/Month | 1979/6 |
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| Article | 報告 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」RI心血管造影を, 99mTc赤血球標識用キット (TCK-11) を用いてin vitroで5〜10mCiの99mTcで赤血球を標識する方法 (in vitro標識法) と, 骨シンチグラフィー用のピロリン酸塩化第一スズをあらかじめ投与しておき, 30分後に99mTc-pertechnetateを投与して赤血球をin vivoに標識する方法 (in vivo標識法) の両者で行ない, おのおのを比較した. In vivo法では, 99mTc投与後, 標識が安定するまで6分を要し, シンチカメラ像は, 血管外に漏出する99mTcのため, in vitro法より劣っていた. In vitro法では標識は安定しておりin vivo法より優れていたが, 他方, 標識操作は煩雑であった. 臨床診断学的には. 両法とも, 99mTc-pertechnetateや99mTc人血清アルブミンを用いる方法より優れており, in vitro法を場合に応じて使い分けることにより, 良質な心血管造影が得られることを論じた. |
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| Practice | 臨床医学：一般 |
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| Keywords | RI cardioangiography, 99mTc RBC labeling, In vitro labeling, In vivo labeling |
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| English |
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| Title | Blood Cell Labeling with Technetium-99m (6) Radionuclide Cardioangiography with Technetium-99m Red Blood Cells Labeled In Vivo and In Vitro |
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| Subtitle | Short Communication |
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| Authors | Tatsumi UCHIDA*, Kazuo MACHII*, Kenji OHWADA*, Susumu FUNAYAMA*, Kiyohiro IKEDA*, Kazuo ONO*, Toshiyuki KIDA**, Shigeo KARIYONE* |
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| Authors(kana) | |
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| Organization | *The First Department of Internal Medicine, and **Department of Radiology, Fukushima Medical College |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 16 |
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| Number | 4 |
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| Page | 563-567 |
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| Year/Month | 1979/6 |
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| Article | Report |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Radionuclide cardioangiography was performed by using 99mTc in vitro and in vivo labeled red blood cells. With in vitro studies, 2 ml of whole blood was incubated with 3 μg of stannous pyrophosphate (TCK-11), followed by removing the supernatant and incubation of 10-15 mCi of 99mTc for 5-10 minutes. After once washing, labeling yield of 48.9+-22.7% was obtained in 10 studies. The in vivo studies were done with two consecutive intravenous injection, first of "cold" stannous pyrophosphate (Sn-PYP) and then of 99mTc. The labeling reached to plateau 6 minutes after injection of 99mTc and labeling yield was 81.1+-20.0%. A comparison was performed between in vivo and in vitro studies. The in vitro method revealed superior images, better intravascular retention and lower background than in vivo method. It is discussed both methods are suitable for radionuclide cardioangiography. |
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| Practice | Clinical medicine |
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| Keywords | RI cardioangiography, 99mTc RBC labeling, In vitro labeling, In vivo labeling |
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