Japanese
Title慢性甲状腺炎 (橋本病) における甲状腺シンチグラムと病理像との対比
Subtitle原著
Authors熊野町子*, 楢林和之*, 井上善夫**, 西山章次**, 岡田聡***, 武田善樹***, 前田知穂****
Authors(kana)
Organization*兵庫県立病院がんセンター放射線科, **神戸大学医学部放射線科, ***神戸大学医学部附属病院中検病理, ****京都府立医科大学放射線医学教室
Journal核医学
Volume15
Number8
Page1143-1149
Year/Month1978/12
Article原著
Publisher日本核医学会
Abstract「要旨」慢性甲状腺炎 (橋本病) のシンチグラム所見は多様性を示し, その診断は困難なことがある. そこで, 病理組織学的に慢性甲状腺炎と診断された患者51症例の甲状腺RI検査所見と組織所見とを対比してみた. シンチグラムはびまん性腫大型と不均一分布型に分類し, さらに不均一分布型を多発欠損型, 単一欠損型, 局所集積型に分類した. これらの各型と組織所見とを対比した結果, びまん性腫大型では甲状腺実質の障害像は軽度で, 間質の病変も軽度であり, 131I-摂取率は高値を示した. 不均一分布型では, シンチグラムの欠損像は甲状腺実質障害像と相関して出現しており, 間質の線維化の高度なものほど131I-摂取率は低値を示した. シンチグラムと131I-摂取率を総括的に詳細に観察すれば, 慢性甲状腺炎の病態像の把握がより可能になるものと考えられる.
Practice臨床医学:一般
KeywordsChronic thyroidits (Hashimoto's disease), scintigram, 131I-uptake rate, Pathohistology
English
TitleCorrelation between Scintigram and Pathology of the Chronic Thyroiditis (Hashimoto's Disease)
SubtitleOriginal Articles
AuthorsMachiko KUMANO*, Kazuyuki NARABAYASHI*, Shoji NISHIYAMA**, Yoshio INOUE**, Satoshi OKADA***, Zenju TAKEDA***, Tomoho MAEDA****
Authors(kana)
Organization*Department of Radiology, Hyogo Cancer Hospital, **Department of Radiology, Kobe University School of Medicine, ***Division of Pathology, Department of Central Clinical Laboratory, Kobe University School of Medicine, ****Department of Radiology, Kyoto Prefectual Medical College
JournalThe Japanese Journal of nuclear medicine
Volume15
Number8
Page1143-1149
Year/Month1978/12
ArticleOriginal article
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] It is often difficult to establish diagnosis of chronic thyroiditis (Hashimoto's disease) scintigraphically, since the scintigrams take various patterns. In the present paper, the correlation among scintigrams, 131I-uptake rates and histologic findings were studied on 51 cases of the histologically confirmed chronic thyroiditis. The scintigrams of chronic thyroiditis were classified into the diffuse hypertrophic and the mottled hypertrophic type. The latter was further grouped into three subtypes ; those with multidefects, with single defect and with local accumulation. In the diffuse hypertrophic type, histological examination revealed a mild degree of parenchymal degeneration and interstitial fibrosis and the 131I-uptake rate was usually elevated. In the mottled hypertrophic type, the areas showing the parenchymal degeneration were presented as a defect in the scintigrams, and the 131I-uptake was variable. Detailed examination of the scintigrams and 131I-uptake rate might offer useful information for the assessment of the pathophysiology of the chronic thyroiditis.
PracticeClinical medicine
KeywordsChronic thyroidits (Hashimoto's disease), scintigram, 131I-uptake rate, Pathohistology

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