| Japanese |
|---|
| Title | 99mTc標識リン酸化合物による骨シンチグラフィの臨床的検討 (III) - 代謝性骨疾患, 骨異形成症について - |
|---|
| Subtitle | 原著 |
|---|
| Authors | 山本逸雄 |
|---|
| Authors(kana) | |
|---|
| Organization | *京都大学医学部放射線・核医学科 |
|---|
| Journal | 核医学 |
|---|
| Volume | 15 |
|---|
| Number | 8 |
|---|
| Page | 1111-1124 |
|---|
| Year/Month | 1978/12 |
|---|
| Article | 原著 |
|---|
| Publisher | 日本核医学会 |
|---|
| Abstract | 「要旨」副甲状腺疾患, 骨異形成症等について全身骨シンチグラフィを施行し, その臨床的意義を検討した. 副甲状腺機能亢進症において, 骨型の例では全例に, 頭蓋および全身骨に強い集積を認めたが腎結石型では, 骨シンチグラムは正常であった. 副甲状腺機能低下症においては, 骨への集積の低下が認められた. 腎性骨異栄養症の2例において異所性石灰巣の発見に有用であった. 骨軟化症においては全身骨へのとりこみの亢進が認められた. 甲状腺髄様癌例では全身骨のとりこみに変化は認められなかったが, 甲状腺の腫瘍へのとりこみを認めた. 骨粗鬆症例においては, 対照例との間に骨シンチグラム上相違を指摘し得なかった. 骨シンチグラムの集積の程度と, 47Ca静注試験によるカルシウムプール値, 骨形成率値との間に相関がみられ, 骨シンチグラフィは, 骨代謝判定に有用と思われた. |
|---|
| Practice | 臨床医学：一般 |
|---|
| Keywords | Bone Scintigraphy, Metabolic Bone Disease, 47Ca Kinetic Study, Bone Dysplasia |
|---|
| English |
|---|
| Title | Clinical Evaluation of Bone Scintigraphy with 99mTc-Labeled Phosphate Compounds (part three) - Metabolic Bone Diseases and Bone Dysplasias - |
|---|
| Subtitle | Original Articles |
|---|
| Authors | Itsuo YAMAMOTO* |
|---|
| Authors(kana) | |
|---|
| Organization | *Department of Radiology and Nuclear Medicine, Kyoto University Hospital |
|---|
| Journal | The Japanese Journal of nuclear medicine |
|---|
| Volume | 15 |
|---|
| Number | 8 |
|---|
| Page | 1111-1124 |
|---|
| Year/Month | 1978/12 |
|---|
| Article | Original article |
|---|
| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
|---|
| Abstract | [Summary] Bone scintigraphy with 99mTc-labeled phosphate compounds were performed on metabolic bone diseases and bone dysplasias and the bone scintigrams were evaluated by comparing with X-ray examinations and / or calcium kinetic studies using 47Ca performed on the same patients. On primary hyperparathyroidism, bone scintigraphy correlated well with both of X-ray examination and 47Ca kintetic study. Cases with skeletal changes due to hyper secretion of parathyroid hormone on X-ray examination and with highly elevated values for serum alkaline phosphatase, showed significantly increases accumulation of 99mTc-EHDP on the skull and other bones and also had increased calcium pool and bone accretion rate on calcium kinetic study. On the other hand, cases with no skeletal changes on X-ray examination and with normal values for serum alkaline phosphatase showed also no abnormal findings on bone scintigraphy and calcium kinetic study. In cases with hypoparathyroidism, calcium pool and bone accretion rate were decreased and bone scintigraphy showed decreased uptake of radionuclide by the skeleton. In osteomalacia, calcium pool and bone accretion rate were significantly increased and bone scintigraphy also showed increased uptake of 99mTc-EHDP by the whole skeleton. In osteoporosis and medullary carcinoma of the thyroid, calcium kinetic study and bone scintigraphy showed no abnormal findings. In conclusion, bone scintigraphy correlated well with calcium kinetic study and bone scintigraphy was very useful for the evaluation of metabolic bone diseases. |
|---|
| Practice | Clinical medicine |
|---|
| Keywords | Bone Scintigraphy, Metabolic Bone Disease, 47Ca Kinetic Study, Bone Dysplasia |
|---|