Japanese
Title131I投与甲状腺癌患者の汗中131Iの測定
Subtitle短報
Authors小原健1), 西沢邦秀2), 大島統男3), 前越久4), 折戸武郎5), 渡辺令5)
Authors(kana)
Organization1)名古屋大学医学部放射線医学教室, 2)名古屋大学医学部アイソトープセンター, 3)筑波大学臨床医学系, 4)名古屋大学医学部附属診療放射線技師学校, 5)金沢大学医療短期大学部診療放射線学科, 6)名古屋鉄道病院
Journal核医学
Volume15
Number7
Page1049-1054
Year/Month1978/10
Article報告
Publisher日本核医学会
Abstract「緒言」治療に用いる131Iは大量に投与されることが多い上に, 環境中の許容レベルが低いため, 131I投与患者の排泄物による環境汚染の適切な評価が待たれている. これまでわれわれは, 131I投与患者の呼気のモニタリングを行ない, すでに報告した. しかし, 131I投与患者の汗のモニタリングは未だ試みられていない. そこで131I投与患者の汗中へ, どの程度の131Iが漏出し, さらにそれによる空気汚染はどの程度かを知ろうとして, 131I投与患者の汗のモニタリングを行なった. 「研究方法」「1. 体表面への漏出」濾紙 (東洋濾紙No.2) に塩化カルシウムを塗付し, デンケーター中に2週間程度放置してあらかじめ乾燥させておく. 皮膚表面へ漏出した131Iによる汚染を除去するため, 汗採取直前に患者の手掌を蒸留水およびエタノールを含む脱脂綿でスミヤする. これを前スミヤと呼ぶ. Fig.1 (1) のごとく乾燥濾紙を秤量後アクリル製円筒に設置してデシケーター中に保存しておき, 使用直前にデシケーターよりとり出し直ちに, 濾紙を手掌皮膚に密着させ, その上をビニールで覆い密封した.
Practice臨床医学:一般
KeywordsRadioiodine in perspiration, air contamination, radioiodine monitoring.
English
TitleMonitoring of 131I in Perspiration of Thyroid Carcinoma Patients Administered 131I for Therapy
Subtitle
AuthorsK.OHARA1), K.NISIZAWA2), M.OSHIMA3), H.MAEKOSHI4), T.ORITO4), T.WATANABE5)
Authors(kana)
Organization1)Department of Radiology, Faculty of Medicine, Nagoya University, 2)Radioisotope Center and Department of Radiology, Faculty of Medicine, Nagoya University, 3)Institute of Clinical Medicine, The University of Tsukuba, 4)Radiological Technician's School Affiliated to Faculty of Medicine, Nagoya University, 5)Department of Radiology, Nagoya National Railway Hospital
JournalThe Japanese Journal of nuclear medicine
Volume15
Number7
Page1049-1054
Year/Month1978/10
ArticleReport
PublisherTHE JAPANESE SOCIETY OF NUCLEAR MEDICINE
Abstract[Summary] The monitoring of the radioiodine concentration in perspiration was carried out for a thyroid carcinoma patient administered orally 131I of 30 mCi for 8 days and for a patient of 50 mCi for 9 days, respectively. The level of air contamination through perspiration was also evaluated. The perspiration was sampled using a dried filter paper coated calcium chloride during one hour and the skin surface of patients was smeared both before and after sampling in order to decontaminate the adhered skin activity. The peak activity of the patient given 50 mCi was reached at one day after administration and was 32 nCi per gram per hour. The total activity of 131I excreted on the body surface during one hour was estimated using the peak activity multiplied by the mean insensible perspiration of 900 gram per day for Japanese. The maximum excretion rate to the administered activity was 2.4×10-5 per hour. The radioiodine in water vapour through perspiration was trapped by the filter paper during one hour for the patient given 30 mCi. The activity of filter paper ranged from 0.5% to 1.8% of the activity of after smear. The maximum discharge rate of 131I which discharges directly into air through perspiration of 131I patients ranged 4.32×10-7 per hour to 1.2×10-7 per hour of the administered dose.
PracticeClinical medicine
KeywordsRadioiodine in perspiration, air contamination, radioiodine monitoring.

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