| Japanese |
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| Title | 99mTc標識リン酸化合物による骨シンチグラフィの臨床的検討 (II) - 原発性骨腫瘍について - |
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| Subtitle | 原著 |
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| Authors | 山本逸雄* |
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| Authors(kana) | |
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| Organization | *京都大学放射線・核医学科 |
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| Journal | 核医学 |
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| Volume | 15 |
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| Number | 7 |
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| Page | 969-979 |
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| Year/Month | 1978/10 |
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| Article | 原著 |
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| Publisher | 日本核医学会 |
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| Abstract | 「要旨」: 原発性骨腫瘍の151例に99mTc標識リン酸化合物による骨シンチグラフィを施行し, その臨床的意義を検討した. 悪性の骨腫瘍は強い集積を示し, 良性の骨腫瘍では, 集積が弱い傾向があったが, 例外が認められた. 集積の機序として, 正常の骨の反応と, 腫瘍骨への集積の2つに分けて考えるべきと思われた. 骨肉腫の転移においては, 骨形成性の骨肉腫において異常集積を示したが骨溶解性の骨肉腫においては集積は認めなかった. 多発性外骨症の経過観察に骨シンチグラフィは有用であり, 強い集積を示す例は悪性化の疑いが強いと思われた. 線維性異形成例は全例強い集積を認め, 特徴的であった. 骨髄腫例においては, 集積を示す例と, 示さない例とがあった. |
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| Practice | 臨床医学：一般 |
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| Keywords | Bone Scintigraphy, 99mTc-Labeled Phosphate Compounds Primary Bone Tumor |
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| English |
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| Title | Clinical Evaluation of Bone Scintigraphy with 99mTc-Labeled Phosphate Compounds (II)....Primary Bone Tumor and Tumor-like Lesion.... |
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| Subtitle | Original Articles |
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| Authors | Itsuo YAMAMOTO |
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| Authors(kana) | |
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| Organization | Department of Radiology and Nuclear Medicine, Kyoto University Hospital |
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| Journal | The Japanese Journal of nuclear medicine |
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| Volume | 15 |
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| Number | 7 |
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| Page | 969-979 |
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| Year/Month | 1978/10 |
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| Article | Original article |
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| Publisher | THE JAPANESE SOCIETY OF NUCLEAR MEDICINE |
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| Abstract | [Summary] Bone scintigraphy with 99mTc-labeled phosphate compounds (mainly 99mTc-EHDP) was performed on 151 cases with a primary bone tumor or tumor-like lesion. Malignant bone tumors usually showed high uptake, but some benign bone tumors also showed high uptake. Two types of bone scintigrams for primary bone tumors were recognized ; the one with a central defect, the other with a diffuse accumulation in the center of the tumor. In cases of lung metastasis from osteogenic sarcoma, the osteolytic osteosarcoma showed no accumulation of 99mTc-EHDP, but the osteosclelotic osteosarcoma showed extensive accumulations into the metastatic foci. In cases of exostosis, bone scintigraphy was useful for the evaluation of tumor growth, because malignant changes were accompanied by intensive uptakes of 99mTc-EHDP. Bone scintigrams of fibrous dysplasia always showed significantly increased accumulations of 99mTc-EHDP into the center of tumors. In cases of plasma cell myeloma, bone scintigraphy showed no or slight increase of an accumulation of 99mTc-EHDP, but 2 of 22 cases showed significantly increased accumulations into the lesions missed by X-ray examinations. |
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| Practice | Clinical medicine |
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| Keywords | Bone Scintigraphy, 99mTc-Labeled Phosphate Compounds Primary Bone Tumor |
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